Tubulin, the subunit protein of microtubules, is an α/β heterodimer. In many organisms, both
α and β exist in numerous isotypic forms encoded by different genes. In addition, both α and …

The mammalian cell cytoskeleton consists of a diverse group of fibrillar elements that play a
pivotal role in mediating a number of digestive and nondigestive cell functions, including …

The oriented peptide library technique was used to investigate the peptide-binding
specificities of nine PDZ domains. Each PDZ domain selected peptides with hydrophobic …

In axons, organelles move away from (anterograde) and toward (retrograde) the cell body
along microtubules. Previous studies have provided compelling evidence that conventional …

In Drosophila melanogaster, a testis-specific β-tubulin (β2) is required for spermatogenesis.
A sequence motif was identified in carboxyl termini of axonemal β-tubulins in diverse taxa …

Smooth muscle plays a prominent role in many fundamental processes and diseases, yet
our understanding of the transcriptional network regulating its development is very limited …

We used transgenic analysis in Drosophila to compare the ability of two structurally similar
alpha-tubulin isoforms to support microtubule assembly in vivo. Our data revealed that even …

Ninefold microtubule symmetry of the eukaryotic basal body and motile axoneme has been
long established [1–3]. In Drosophila, these organelles contain distinct but similar β-tubulin …

We have sought to define the developmental and cellular roles played by differential
expression of distinct β-tubulins. Drosophila β3-tubulin (β3) is a structurally divergent …

Theβ3 tubulingene (βTub60D) is a structural gene expressed during mesoderm
development from the extended germ band stage onward. Expression within the individual …