Therapeutic potential of quercetin: new insights and perspectives for human health

B Salehi, L Machin, L Monzote, J Sharifi-Rad… - ACS …, 2020 - ACS Publications
Quercetin (Que) and its derivatives are naturally occurring phytochemicals with promising
bioactive effects. The antidiabetic, anti-inflammatory, antioxidant, antimicrobial, anti …

The E-cadherin and N-cadherin switch in epithelial-to-mesenchymal transition: signaling, therapeutic implications, and challenges

CY Loh, JY Chai, TF Tang, WF Wong, G Sethi… - Cells, 2019 - mdpi.com
Epithelial-to-Mesenchymal Transition (EMT) has been shown to be crucial in tumorigenesis
where the EMT program enhances metastasis, chemoresistance and tumor stemness. Due …

Phenolic composition, antioxidant potential and health benefits of citrus peel

B Singh, JP Singh, A Kaur, N Singh - Food Research International, 2020 - Elsevier
Citrus peel (CP) forms around 40–50% of the total fruit mass but is generally thought to be a
waste. However, it is a substantial source of naturally occurring health enhancing …

A review on flavonoid apigenin: Dietary intake, ADME, antimicrobial effects, and interactions with human gut microbiota

M Wang, J Firrman, LS Liu… - BioMed research …, 2019 - Wiley Online Library
Apigenin is a flavonoid of low toxicity and multiple beneficial bioactivities. Published reviews
all focused on the findings using eukaryotic cells, animal models, or epidemiological studies …

[HTML][HTML] The role of metabolism (and the microbiome) in defining the clinical efficacy of dietary flavonoids

A Cassidy, AM Minihane - The American journal of clinical nutrition, 2017 - Elsevier
At a population level, there is growing evidence of the beneficial effects of dietary flavonoids
on health. However, there is extensive heterogeneity in the response to increased intake …

[HTML][HTML] Benefits of polyphenols on gut microbiota and implications in human health

F Cardona, C Andrés-Lacueva, S Tulipani… - The Journal of nutritional …, 2013 - Elsevier
The biological properties of dietary polyphenols are greatly dependent on their
bioavailability that, in turn, is largely influenced by their degree of polymerization. The gut …

Chemistry and biochemistry of dietary polyphenols

R Tsao - Nutrients, 2010 - mdpi.com
Polyphenols are the biggest group of phytochemicals, and many of them have been found in
plant-based foods. Polyphenol-rich diets have been linked to many health benefits. This …

Bioavailability of bioactive food compounds: A challenging journey to bioefficacy

MJ Rein, M Renouf, C Cruz‐Hernandez… - British journal of …, 2013 - Wiley Online Library
Bioavailability is a key step in ensuring bioefficacy of bioactive food compounds or oral
drugs. Bioavailability is a complex process involving several different stages: liberation …

Enhancement of bioavailability and bioactivity of diet-derived flavonoids by application of nanotechnology: A review

H Teng, Y Zheng, H Cao, Q Huang… - Critical Reviews in …, 2023 - Taylor & Francis
Flavonoids, which are a class of polyphenols widely existing in food and medicine, have
enormous pharmacological effects. The functional properties of flavonoids are mainly …

Flavonoids as anti-inflammatory agents

M Serafini, I Peluso, A Raguzzini - Proceedings of the Nutrition …, 2010 - cambridge.org
Epidemiological evidence suggests that a high intake of plant foods is associated with lower
risk of chronic diseases. However, the mechanism of action and the components involved in …