COVID-19, hyperglycemia, and new-onset diabetes

K Khunti, S Del Prato, C Mathieu, SE Kahn… - Diabetes …, 2021 - Am Diabetes Assoc
Certain chronic comorbidities, including diabetes, are highly prevalent in people with
coronavirus disease 2019 (COVID-19) and are associated with an increased risk of severe …

COVID-19 and metabolic disease: mechanisms and clinical management

C Steenblock, PEH Schwarz, B Ludwig… - The lancet Diabetes & …, 2021 - thelancet.com
Up to 50% of the people who have died from COVID-19 had metabolic and vascular
disorders. Notably, there are many direct links between COVID-19 and the metabolic and …

Acute and long-term disruption of glycometabolic control after SARS-CoV-2 infection

L Montefusco, M Ben Nasr, F D'Addio, C Loretelli… - Nature …, 2021 - nature.com
Patients with coronavirus disease 2019 (COVID-19) are reported to have a greater
prevalence of hyperglycaemia. Cytokine release as a consequence of severe acute …

SARS-CoV-2 infects and replicates in cells of the human endocrine and exocrine pancreas

JA Müller, R Groß, C Conzelmann, J Krüger… - Nature …, 2021 - nature.com
Infection-related diabetes can arise as a result of virus-associated β-cell destruction. Clinical
data suggest that the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) …

[PDF][PDF] SARS-CoV-2 infects human pancreatic β cells and elicits β cell impairment

CT Wu, PV Lidsky, Y Xiao, IT Lee, R Cheng… - Cell metabolism, 2021 - cell.com
Emerging evidence points toward an intricate relationship between the pandemic of
coronavirus disease 2019 (COVID-19) and diabetes. While preexisting diabetes is …

Pathogenic mechanisms of post-acute sequelae of SARS-CoV-2 infection (PASC)

ZA Sherif, CR Gomez, TJ Connors, TJ Henrich… - Elife, 2023 - elifesciences.org
COVID-19, with persistent and new onset of symptoms such as fatigue, post-exertional
malaise, and cognitive dysfunction that last for months and impact everyday functioning, is …

[PDF][PDF] Hyperglycemia in acute COVID-19 is characterized by insulin resistance and adipose tissue infectivity by SARS-CoV-2

M Reiterer, M Rajan, N Gómez-Banoy, JD Lau… - Cell metabolism, 2021 - cell.com
Individuals infected with SARS-CoV-2 who also display hyperglycemia suffer from longer
hospital stays, higher risk of developing acute respiratory distress syndrome (ARDS), and …

Post-acute effects of SARS-CoV-2 infection in individuals not requiring hospital admission: a Danish population-based cohort study

LC Lund, J Hallas, H Nielsen, A Koch… - The Lancet Infectious …, 2021 - thelancet.com
Background Individuals admitted to hospital for COVID-19 might have persisting symptoms
(so-called long COVID) and delayed complications after discharge. However, little is known …

[HTML][HTML] COVID-19 and diabetes: understanding the interrelationship and risks for a severe course

CP Landstra, EJP de Koning - Frontiers in endocrinology, 2021 - frontiersin.org
The relationship between COVID-19 and diabetes mellitus is complicated and bidirectional.
On the one hand, diabetes mellitus is considered one of the most important risk factors for a …

Trends in antidiabetic drug discovery: FDA approved drugs, new drugs in clinical trials and global sales

AD Dahlén, G Dashi, I Maslov, MM Attwood… - Frontiers in …, 2022 - frontiersin.org
Type 2 diabetes mellitus (T2DM) continues to be a substantial medical problem due to its
increasing global prevalence and because chronic hyperglycemic states are closely linked …