Adhesion molecules and atherosclerosis

S Blankenberg, S Barbaux, L Tiret - Atherosclerosis, 2003 - Elsevier
One early phase of atherosclerosis involves the recruitment of inflammatory cells from the
circulation and their transendothelial migration. This process is predominantly mediated by …

ICAM-1 signaling in endothelial cells

C Lawson, S Wolf - Pharmacological reports, 2009 - Elsevier
Abstract Intercellular adhesion molecule-1 (ICAM-1; CD54) is a 90 kDa member of the
immunoglobulin (Ig) superfamily and is critical for the firm arrest and transmigration of …

Inflammation in peripheral artery disease

G Brevetti, G Giugliano, L Brevetti, WR Hiatt - Circulation, 2010 - Am Heart Assoc
Peripheral artery disease (PAD), which consists of partial or complete obstruction of the
arteries in the lower limbs, is one of the most common manifestations of atherosclerosis …

Endothelial dysfunction: a key to the pathophysiology and natural history of peripheral arterial disease?

G Brevetti, V Schiano, M Chiariello - Atherosclerosis, 2008 - Elsevier
Dysfunctional endothelium plays a crucial role in all stages of atherosclerosis and thus the
accurate assessment of this organ is a valuable tool, especially if such assessments are …

Proinflammatory genetic profiles in subjects with history of ischemic stroke

A Flex, E Gaetani, P Papaleo, G Straface, AS Proia… - Stroke, 2004 - Am Heart Assoc
Background and Purpose—Proinflammatory genetic profiles, resulting from the combination
of single nucleotide polymorphisms in genes encoding inflammatory molecules, may …

Synergistic effect of− 174 G/C polymorphism of the interleukin-6 gene promoter and 469 E/K polymorphism of the intercellular adhesion molecule-1 gene in Italian …

R Pola, A Flex, E Gaetani, R Flore, M Serricchio, P Pola - Stroke, 2003 - Am Heart Assoc
Background and Purpose—Interleukin-6 (IL-6) and intercellular adhesion molecule-1 (ICAM-
1) are involved in the pathogenetic mechanisms responsible for several ischemic …

Selected gene polymorphisms and their interaction with maternal smoking, as risk factors for gastroschisis

CP Torfs, RE Christianson… - … Research Part A …, 2006 - Wiley Online Library
BACKGROUND: Gastroschisis is a severe birth defect in which the infant is born with a
portion of the intestines extruding through a small tear in the abdominal wall, usually to the …

Genetics of peripheral artery disease

NJ Leeper, IJ Kullo, JP Cooke - Circulation, 2012 - Am Heart Assoc
Broadly defined, peripheral vascular disease refers to disease of the extracardiac blood
vessels, including diseases of the arteries, veins, and lymphatics. Peripheral arterial disease …

Molecular genetics of atherosclerosis

H Roy, S Bhardwaj, S Yla-Herttuala - Human genetics, 2009 - Springer
Atherosclerosis is a complex multifocal arterial disease involving interactions of multiple
genetic and environmental factors. Advances in techniques of molecular genetics have …

Cellular adhesion molecules and peripheral arterial disease

G Brevetti, V Schiano, M Chiariello - Vascular Medicine, 2006 - journals.sagepub.com
Cellular adhesion molecules (CAMs), by mediating the recruitment of circulating leukocytes
to the blood vessel wall and their subsequent migration into the subendothelial spaces, play …