Induction of metastasis, cancer stem cell phenotype, and oncogenic metabolism in cancer cells by ionizing radiation

SY Lee, EK Jeong, MK Ju, HM Jeon, MY Kim, CH Kim… - Molecular cancer, 2017 - Springer
Radiation therapy is one of the major tools of cancer treatment, and is widely used for a
variety of malignant tumours. Radiotherapy causes DNA damage directly by ionization or …

[HTML][HTML] Progress of exosomes in the diagnosis and treatment of lung cancer

K Xu, C Zhang, T Du, ANA Gabriel, X Wang, X Li… - Biomedicine & …, 2021 - Elsevier
The incidence and mortality of lung cancer account for first place all over the world. Lung
cancer lacks early diagnostic biomarkers; lung cancer patients are usually diagnosed in …

Cellular pathways in response to ionizing radiation and their targetability for tumor radiosensitization

P Maier, L Hartmann, F Wenz, C Herskind - International journal of …, 2016 - mdpi.com
During the last few decades, improvements in the planning and application of radiotherapy
in combination with surgery and chemotherapy resulted in increased survival rates of tumor …

Radiosensitising cancer using phosphatidylinositol-3-kinase (PI3K), protein kinase B (AKT) or mammalian target of rapamycin (mTOR) inhibitors

K Wanigasooriya, R Tyler, JD Barros-Silva, Y Sinha… - Cancers, 2020 - mdpi.com
Radiotherapy is routinely used as a neoadjuvant, adjuvant or palliative treatment in various
cancers. There is significant variation in clinical response to radiotherapy with or without …

Molecular stressors engender protein connectivity dysfunction through aberrant N-glycosylation of a chaperone

P Yan, HJ Patel, S Sharma, A Corben, T Wang… - Cell reports, 2020 - cell.com
Stresses associated with disease may pathologically remodel the proteome by both
increasing interaction strength and altering interaction partners, resulting in proteome-wide …

Defucosylated Anti-Epidermal Growth Factor Receptor Monoclonal Antibody 134-mG2a-f Exerts Antitumor Activities in Mouse Xenograft Models of Dog Epidermal …

N Tateyama, R Nanamiya, T Ohishi, J Takei… - Monoclonal …, 2021 - liebertpub.com
The epidermal growth factor receptor (EGFR) is a type I transmembrane protein, which is a
member of the human epidermal growth factor receptor (HER) family of receptor tyrosine …

EGFR amplification and expression in oral squamous cell carcinoma in young adults

V Costa, LP Kowalski, CM Coutinho-Camillo… - International journal of …, 2018 - Elsevier
The aim of this study was to investigate epidermal growth factor receptor (EGFR) gene
alterations in two groups of patients with oral squamous cell carcinoma (OSCC)(a test group …

Knockdown of Musashi RNA binding proteins decreases radioresistance but enhances cell motility and invasion in triple-negative breast cancer

FM Troschel, A Minte, YM Ismail, A Kamal… - International Journal of …, 2020 - mdpi.com
The therapeutic potential of Musashi (MSI) RNA-binding proteins, important stemness-
associated gene expression regulators, remains insufficiently understood in breast cancer …

A novel 3-miRNA network regulates tumour progression in oral squamous cell carcinoma

A Patel, P Patel, D Mandlik, K Patel, P Malaviya… - Biomarker …, 2023 - Springer
Background Late diagnosis is one of the major confounders in oral squamous cell
carcinoma (OSCC). Despite recent advances in molecular diagnostics, no disease-specific …

Survival benefit of thoracic radiotherapy plus EGFR-TKIs in patients with non-oligometastatic advanced non-small-cell lung cancer: a single-center retrospective study

F Zhou, Y Qin, X Liu, J Huang, B Wu… - Therapeutic …, 2023 - journals.sagepub.com
Objectives: The study aims to evaluate the efficacy and safety of thoracic radiotherapy in
epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor (TKI)-treated patients with …