Siah1 in cancer and nervous system diseases
H Zhang, J Wang, Y Ge, M Ye, X Jin - Oncology reports, 2022 - spandidos-publications.com
The dysregulation of the ubiquitin‑proteasome system will result in the abnormal
accumulation and dysfunction of proteins, thus leading to severe diseases. Seven in …
accumulation and dysfunction of proteins, thus leading to severe diseases. Seven in …
Protein stability regulation in osteosarcoma: the ubiquitin-like modifications and glycosylation as mediators of tumor growth and as targets for therapy
J Di Gregorio, L Di Giuseppe, S Terreri, M Rossi… - Cells, 2024 - mdpi.com
The identification of new therapeutic targets and the development of innovative therapeutic
approaches are the most important challenges for osteosarcoma treatment. In fact, despite …
approaches are the most important challenges for osteosarcoma treatment. In fact, despite …
Notoginsenoside R1 counteracts mesenchymal stem cell-evoked oncogenesis and doxorubicin resistance in osteosarcoma cells by blocking IL-6 secretion-induced …
M Lu, K Xie, X Lu, L Lu, Y Shi, Y Tang - Investigational New Drugs, 2021 - Springer
Tumor microenvironment is a critical participant in the initiation, progression and drug
resistance of carcinomas, including osteosarcoma. Notoginsenoside R1 (NGR1) is a …
resistance of carcinomas, including osteosarcoma. Notoginsenoside R1 (NGR1) is a …
Chemoresistance-related stem cell signaling in osteosarcoma and its plausible contribution to poor therapeutic response: a discussion that still matters
SR Martins-Neves, G Sampaio-Ribeiro… - International journal of …, 2022 - mdpi.com
Osteosarcoma is amongst the most prevalent bone sarcomas and majorly afflicts children
and adolescents. Therapeutic regimens based on the triad of doxorubicin, cisplatin and …
and adolescents. Therapeutic regimens based on the triad of doxorubicin, cisplatin and …
Altered Transcriptional Regulation of Glycolysis in Circulating CD8+ T Cells of Rheumatoid Arthritis Patients
S Harshan, P Dey, S Raghunathan - Genes, 2022 - mdpi.com
Peripheral T lymphocytes of rheumatoid arthritis (RA) patients show pathological changes in
their metabolic pathways, especially glycolysis. These changes may drive the increased …
their metabolic pathways, especially glycolysis. These changes may drive the increased …
The Transcription Factors Zeb1 and Snail Induce Cell Malignancy and Cancer Stem Cell Phenotype in Prostate Cells, Increasing Androgen Synthesis Capacity and …
F López-Moncada, EA Castellón… - Cancer Stem Cell Markers …, 2023 - Springer
Prostate cancer (PCa) incidence has increased during the last decades, becoming one of
the leading causes of death by cancer in men worldwide. During an extended period of …
the leading causes of death by cancer in men worldwide. During an extended period of …
Quantitative phosphoproteomic analysis reveals chemoresistance-related proteins and signaling pathways induced by rhIL-6 in human osteosarcoma cells
R Zhang, H Wang, E Li, Y Wu, Y Wen, C Li… - Cancer Cell …, 2021 - Springer
Background IL-6 plays a pivotal role in resistance to chemotherapeutics, including
lobaplatin. However, the underlying mechanisms are still unclear. This study was to …
lobaplatin. However, the underlying mechanisms are still unclear. This study was to …
Oncogenic functions of ZEB1 in pediatric solid cancers: interplays with microRNAs and long noncoding RNAs
The transcription factor Zinc finger E-box binding 1 (ZEB1) displays a range of regulatory
activities in cell function and embryonic development, including driving epithelial …
activities in cell function and embryonic development, including driving epithelial …
Comprehensive bioinformatics analysis reveals the oncogenic role of FoxM1 and its impact on prognosis, immune microenvironment, and drug sensitivity in …
S Shi, Q Wang, X Du - Journal of Applied Genetics, 2023 - Springer
Osteosarcoma, a highly malignant bone tumor primarily affecting adolescents, presents a
significant challenge in cancer therapy due to its resistance to chemotherapy. This study …
significant challenge in cancer therapy due to its resistance to chemotherapy. This study …
[PDF][PDF] LncRNA LINC01772 promotes metastasis and EMT process in cervical cancer by sponging miR-3611 to relieve ZEB1
T Ma, F Wang, X Wang - Biocell, 2019 - cdn.techscience.cn
Cervical cancer (CC), has been identified as one of the most frequent malignant tumors all
over the world, with high mortality in females. A growing number of investigations have …
over the world, with high mortality in females. A growing number of investigations have …