Role of inositols and inositol phosphates in energy metabolism

S Chatree, N Thongmaen, K Tantivejkul, C Sitticharoon… - Molecules, 2020 - mdpi.com
Recently, inositols, especially myo-inositol and inositol hexakisphosphate, also known as
phytic acid or IP6, with their biological activities received much attention for their role in …

Adipocyte lipolysis: from molecular mechanisms of regulation to disease and therapeutics

A Yang, EP Mottillo - Biochemical Journal, 2020 - portlandpress.com
Fatty acids (FAs) are stored safely in the form of triacylglycerol (TAG) in lipid droplet (LD)
organelles by professional storage cells called adipocytes. These lipids are mobilized …

Regulation of NAD+ metabolism in aging and disease

X Chu, RP Raju - Metabolism, 2022 - Elsevier
More than a century after discovering NAD+, information is still evolving on the role of this
molecule in health and diseases. The biological functions of NAD+ and NAD+ precursors …

Perilipins at a glance

CP Najt, M Devarajan, DG Mashek - Journal of cell science, 2022 - journals.biologists.com
Lipid droplets (LDs) are ubiquitous organelles that store and supply lipids for energy
metabolism, membrane synthesis and production of lipid-derived signaling molecules. While …

[HTML][HTML] Lipophagy: molecular mechanisms and implications in metabolic disorders

DW Shin - Molecules and cells, 2020 - Elsevier
Autophagy is an intracellular degradation system that breaks down damaged organelles or
damaged proteins using intracellular lysosomes. Recent studies have also revealed that …

Adipogenesis: a necessary but harmful strategy

ME Hafidi, M Buelna-Chontal… - International journal of …, 2019 - mdpi.com
Obesity is considered to significantly increase the risk of the development of a vast range of
metabolic diseases. However, adipogenesis is a complex physiological process, necessary …

Molecular mechanisms of perilipin protein function in lipid droplet metabolism

E Griseti, AA Bello, E Bieth, B Sabbagh… - FEBS …, 2024 - Wiley Online Library
Perilipins are abundant lipid droplet (LD) proteins present in all metazoans and also in
Amoebozoa and fungi. Humans express five perilipins, which share a similar domain …

Structural basis for glycerol efflux and selectivity of human aquaporin 7

SW de Mare, R Venskutonytė, S Eltschkner… - Structure, 2020 - cell.com
Summary The aquaglyceroporin 7 (AQP7) facilitates permeation of glycerol through cell
membranes and is crucial for lipid metabolism in humans. Glycerol efflux in human …

Dysregulation of lipid metabolism and appearance of slow myofiber-specific isoforms accompany the development of Wooden Breast myopathy in modern broiler …

MB Papah, B Abasht - Scientific reports, 2019 - nature.com
Previous transcriptomic studies have hypothesized the occurrence of slow myofiber-
phenotype, and dysregulation of lipid metabolism as being associated with the development …

Cellular communication through extracellular vesicles and lipid droplets

I Amarasinghe, W Phillips, AF Hill… - Journal of …, 2023 - Wiley Online Library
Cellular communication is essential for effective coordination of biological processes. One
major form of intercellular communication occurs via the release of extracellular vesicles …