Plague, caused by the bacterial pathogen Yersinia pestis, is a vector-borne disease that has
caused millions of human deaths over several centuries. Presently, human plague infections …

Fimbriae are long filamentous polymeric protein structures located upon the surface of
bacteria. Often implicated in pathogenicity, the biosynthesis and function of fimbriae has …

Body temperature is maintained at around 37° C in humans, but may rise to 40° C or more
during high‐grade fever, which occurs in most adults who are seriously ill. However …

Yersinia pestis is the cause of plague, historically known as the “Black Death”. Marmota
himalayana in the Qinghai-Tibet Plateau (QTP) natural plague focus is the primary host in …

The pathogenic bacterium Yersina pestis is protected from macrophage engulfment by a
capsule like antigen, F1, formed of long polymers of the monomer protein, Caf1. However …

Cellular lysates capable of transcription and translation have become valuable tools for
prototyping genetic circuits, screening engineered functional parts, and producing biological …

Rapid detection of Yersinia pestis, the causative agent of plague, is essential during field
investigations to enable prompt control measures for prevention of the spread of the …

Outer membrane vesicles (OMVs) are nanostructures that are spontaneously produced by
Gram-negative bacteria during all phases of growth and often in response to stress. Gram …

Pathogenic bacteria undergo a multitude of interactions with host immune cells to establish
an infection and cause disease. One of these interaction axes involves the formyl peptide …

BACKGROUND T-cells are essential in the mediation of immune responses, helping clear
bacteria, viruses and cancerous cells. T-cells recognise anomalies in the cellular proteome …