In response to major changes in diagnostic algorithms and the publication of mature results
from various large clinical trials, the European Association of Neuro-Oncology (EANO) …

• Early symptoms of brain tumours in adults are non-specific, and patients may present
multiple times to primary care services before they are referred for investigation. Look for …

The most frequent adult-type primary CNS tumours are diffuse gliomas, but a large variety of
rarer CNS tumour types exists. The classification of these tumours is increasingly based on …

Translation of survival benefits observed in glioblastoma clinical trials to populations and to
longer-term survival remains uncertain. We aimed to assess if≥ 2-year survival has …

Glioma is a fatal brain tumor characterized by rapid proliferation and treatment resistance.
Ferroptosis is a newly discovered programmed cell death and plays a crucial role in the …

Purpose Glioma incidence in the US seems to have stabilized over the past 20 years. It's
also not clear whether changes in glioblastoma incidence are associated with glioma …

Background Glioma patients suffer from a wide range of symptoms which influence quality of
life negatively. The aim of this review is to give an overview of symptoms most prevalent in …

Background Primary central nervous system (CNS) tumors are a heterogeneous group of
neoplasms, including benign and malignant tumors. Since there are many heterogeneities …

Background Age is associated with the prognosis of glioma patients, but there is no uniform
standard of age-group classification to evaluate the prognosis of glioma patients. In this …

Ferroptosis is a novel regulated cell death characterized by metabolic disorders and iron-
dependent oxidative destruction of the lipid bilayer. It is primarily caused by the imbalance of …