Middle East medicinal plants in the treatment of diabetes: a review

AM Abu-Odeh, WH Talib - Molecules, 2021 - mdpi.com
Diabetes is a global health problem, and the number of diabetic patients is in continuous
rise. Conventional antidiabetic therapies are associated with high costs and limited …

Ethnobotanical Uses, Phytochemistry and Pharmacology of Different Rheum Species (Polygonaceae): A Review

L Mohtashami, MS Amiri, Z Ayati, M Ramezani… - … Properties of Plant …, 2021 - Springer
Today, there is an increased tendency to use herbal remedies. Rhubarb refers to several
species of the genus Rheum L. in the Polygonaceae family. This species-rich genus is …

The effect of Polygonum hyrcanicum Rech. f. hydroalcoholic extract on oxidative stress and nephropathy in alloxan-induced diabetic mice

H Arabnozari, F Shaki, A Najjari, F Sharifianjazi… - Scientific Reports, 2024 - nature.com
Diabetic nephropathy, characterized by inflammation and oxidative stress, poses a
management challenge. This study investigates the effect of Polygonum hyrcanicum extract …

Depletion of senescent-like neuronal cells alleviates cisplatin-induced peripheral neuropathy in mice

S Acklin, M Zhang, W Du, X Zhao, M Plotkin, J Chang… - Scientific reports, 2020 - nature.com
Chemotherapy-induced peripheral neuropathy is among the most common dose-limiting
adverse effects of cancer treatment, leading to dose reduction and discontinuation of life …

Effects of a standardized extract of Rheum turkestanicum Janischew root on diabetic changes in the kidney, liver and heart of streptozotocin-induced diabetic rats

A Hosseini, H Mollazadeh, MS Amiri… - Biomedicine & …, 2017 - Elsevier
Numerus studies highlighted benefits of natural flavonoids in the management of diabetes.
The present study was aimed to investigate the effects of a high flavonoids containing extract …

Prunella vulgaris L. active components and their hypoglycemic and antinociceptive effects in alloxan-induced diabetic mice

K Raafat, M Wurglics, M Schubert-Zsilavecz - Biomedicine & …, 2016 - Elsevier
Abstract Prunella vulgaris L.(Lamiaceae)(PV) is a herbaceous plant traditionally utilized in
management of diabetes and it has immunomodulatory activity. In this study, acute and …

Anti‐Inflammatory and Antioxidant Activities of Salvia fruticosa: An HPLC Determination of Phenolic Contents

R Boukhary, K Raafat, AI Ghoneim… - Evidence‐Based …, 2016 - Wiley Online Library
Objectives. Salvia fruticosa Mill.(S. fruticosa) is widely used in folk medicine. Accordingly, the
present study was designed to evaluate the antioxidant and anti‐inflammatory activities of S …

Hypoglycemic effects of Prunus cerasus L. pulp and seed extracts on Alloxan-Induced Diabetic Mice with histopathological evaluation

FA Saleh, N El-Darra, K Raafat - Biomedicine & Pharmacotherapy, 2017 - Elsevier
Aim of the study The study was undertaken to investigate the acute and subchronic
hypoglycemic effects of an ethyl acetate (EtAc) extract of red sour cherry (Prunus cerasus) …

Acute and subchronic in-vivo effects of Ferula hermonis L. and Sambucus nigra L. and their potential active isolates in a diabetic mouse model of neuropathic pain

K Raafat, A El-Lakany - BMC Complementary and Alternative Medicine, 2015 - Springer
Abstract Background The prevalence of Diabetes mellitus (DM) is escalating rapidly
worldwide, and associated with micro-and macrovascular complications. Diabetic …

Phytochemical compositions and antidiabetic potentials of Salvia sclarea L. essential oils

K Raafat, J Habib - Journal of oleo science, 2018 - jstage.jst.go.jp
Salvia sclarea (SS) is characterized by its valuable essential oils (Eos) and potent biological
activities. This study aimed at investigating the phytochemical composition of SS Eos …