The plasma membrane is of central importance for defining the closed volume of cells in
contradistinction to the extracellular environment. The plasma membrane not only serves as …

The last decade has seen a rapid expansion of interest in extracellular vesicles (EVs)
released by cells and proposed to mediate intercellular communication in physiological and …

The small Rho-family GTPase Cdc42 is critical for cell polarization and polarizes
spontaneously in absence of upstream spatial cues. Spontaneous polarization is thought to …

Extracellular vesicles (EVs) have emerged as promising biomaterials for the treatment of
different disease. However, only handful types of EVs with clinical transformation potential …

Proteoliposome reconstitution is a standard method to stabilize purified transmembrane
proteins in membranes for structural and functional assays. Here we quantified …

G protein-coupled receptors (GPCRs) play crucial roles in the ability of target organs to
respond to hormonal cues. GPCRs' activation mechanisms have long been considered as a …

Cells secrete extracellular vesicles (EVs) into their microenvironment that act as mediators of
intercellular communication under physiological conditions and in this context also actively …

Lateral diffusion enables efficient interactions between membrane proteins, leading to signal
transmission across the plasma membrane. An open question is how the spatiotemporal …

Pulsed electromagnetic fields (PEMFs) are capable of specifically activating a TRPC1‐
mitochondrial axis underlying cell expansion and mitohormetic survival adaptations. This …

The main advantage of extracellular vesicles (EVs) as a drug carrier system is their low
immunogenicity and internalization by mammalian cells. EVs are often considered a cell …