HLA-G is a molecule that was first known to confer protection to the fetus from destruction by
the immune system of its mother, thus critically contributing to fetal–maternal tolerance. The …

Dendritic cells (DCs) are central players in the initiation and control of responses, regulating
the balance between tolerance and immunity. Tolerogenic DCs are essential in the …

Dendritic cells (DCs) are highly specialized professional antigen-presenting cells that
regulate immune responses, maintaining the balance between tolerance and immunity …

Aging is a physiologic/pathologic process characterized by a progressive impairment of
cellular functions, supported by the alterations of several molecular pathways, leading to an …

HLA‐G is a nonclassical HLA class I molecule. In allogeneic situations such as pregnancy or
allograft transplantation, the expression of HLA‐G has been related to a better acceptance of …

The mononuclear phagocytes (dendritic cells and macrophages) are closely related immune
cells with central roles in anti-infectious defense and maintenance of organ integrity. The …

BACKGROUND AND AIMS As conversion from calcineurin inhibitor to sirolimus (SRL), a
mechanistic target of rapamycin inhibitor (mTOR‐I), has been shown to enhance …

Myeloid checkpoints are receptors on the myeloid cell surface which can mediate inhibitory
signals to modulate anti-tumor immune activities. They can either inhibit cellular …

Both CD4+ and CD8+ Tregs play a critical role in the control of immune responses and
immune tolerance; however, our understanding of CD8+ Tregs is limited while they are …

Inhibitory leukocyte immunoglobulin-like receptors (LILRBs 1–5) transduce signals via
intracellular immunoreceptor tyrosine-based inhibitory motifs that recruit phosphatases to …