Cell membranes with their selective permeability play important functions in the tight control
of molecular exchanges between the cytosol and the extracellular environment as the …

Cell penetrating peptides (CPPs), also known as protein transduction domains (PTDs), first
identified~ 25 years ago, are small, 6–30 amino acid long, synthetic, or naturally occurring …

Liposomes have been used extensively as micro-and nanocarriers for hydrophobic or
hydrophilic molecules. However, conventional liposomes are biodegradable and quickly …

The basic amino acids lysine (Lys) and arginine (Arg) play important roles in membrane
protein activity, the sensing of membrane voltages, and the actions of antimicrobial, toxin …

The cornea is a unique tissue and the most powerful focusing element of the eye, known as
a window to the eye. Infectious or non-infectious diseases might cause severe visual …

The delivery of functional proteins remains a major challenge in advancing biological and
pharmaceutical sciences. Herein, we describe a powerful, simple, and highly effective …

Despite the increasing number of effective therapeutics for eye diseases, their treatment is
still challenging due to the presence of effective barriers protecting eye tissues. Cell …

Membrane disruptive α-helical antimicrobial peptides (AMPs) offer an opportunity to address
multidrug resistance; however, most AMPs are toxic and unstable in serum. These …

Adsorption of arginine-rich positively charged peptides onto neutral zwitterionic
phosphocholine (PC) bilayers is a key step in the translocation of those potent cell …

Ligand-targeted nanoparticles are emerging drug delivery vehicles for cancer therapy. Here,
we demonstrate that the cellular uptake of peptide-targeted liposomes and micelles can be …