Allogeneic hematopoietic cell transplantation involves consideration of both donor and
recipient characteristics to guide the selection of a suitable graft. Sufficient high-resolution …

Juvenile myelomonocytic leukemia (JMML) is a unique, aggressive hematopoietic disorder
of infancy/early childhood caused by excessive proliferation of cells of monocytic and …

Background Hematopoietic stem-cell transplantation (HSCT) is a potentially lifesaving
therapy for several blood cancers and other diseases. For patients without a suitable related …

Objectives: Describe the indications for hematopoietic stem cell transplants. Review the
contraindications to hematopoietic stem cell transplants. Outline the potential complications …

Background Benefits of cord blood transplantation include low rates of relapse and chronic
graft-versus-host disease (GVHD). However, the use of cord blood is rapidly declining …

Background The introduction of donors other than HLA-matched siblings has been a pivotal
change in stem cell transplantation. We aimed to assess the evolution of outcomes within …

BACKGROUND. Delayed hematopoietic recovery is a major drawback of umbilical cord
blood (UCB) transplantation. Transplantation of ex vivo–expanded UCB shortens time to …

Chronic myelogenous leukemia (CML) in children is relatively rare. Because of a lack of
robust clinical study evidence, management of CML in children is not standardized and often …

Outcomes after unmanipulated haploidentical stem cell transplantation (Haplo) and after
unrelated cord blood transplantation (UCBT) are encouraging and have become alternative …

Umbilical cord blood transplantation (UCBT) has been performed in the clinic for over 30
years. The biological and immunological characteristics of umbilical cord blood (UCB) have …