Methyl palmitate: the naturally occurring cardioprotective agent
Cardioprotective agents are compounds that provide heart protection and decrease
cardiotoxicity incidence. Cardiotoxicity is a serious condition that results in diminishing the …
cardiotoxicity incidence. Cardiotoxicity is a serious condition that results in diminishing the …
Modulation of cyclophosphamide-induced cardiotoxicity by methyl palmitate
DS El-Agamy, MA Elkablawy… - Cancer chemotherapy and …, 2017 - Springer
Purpose Cyclophosphamide (CP) is a frequently used anticancer and immunosuppressant
although its use has been associated with severe cardiotoxicity. The present study …
although its use has been associated with severe cardiotoxicity. The present study …
Terretonin as a new protective agent against sepsis-induced acute lung injury: Impact on SIRT1/Nrf2/NF-κBp65/NLRP3 signaling
Simple Summary Acute lung injury (ALI) is a severe inflammatory pulmonary disorder that
still causes a high mortality rate. As the current therapeutic strategies have not been effective …
still causes a high mortality rate. As the current therapeutic strategies have not been effective …
Lutein mitigates cyclophosphamide induced lung and liver injury via NF-κB/MAPK dependent mechanism
AA El-Kholy, MA Elkablawy, DS El-Agamy - Biomedicine & …, 2017 - Elsevier
This study targeted to test the potential protective role of lutein against lung and liver
damage associated with cyclophosphamide (CP) administration. Lutein was given orally for …
damage associated with cyclophosphamide (CP) administration. Lutein was given orally for …
Protective effect of pristimerin against LPS-induced acute lung injury in mice
Pristimerin (Pris) is a triterpenoid derivative obtained from Celastraceae and
Hippocrateaceae families. This compound has been extensively tested for its potent anti …
Hippocrateaceae families. This compound has been extensively tested for its potent anti …
[HTML][HTML] Lutein prevents alcohol-induced liver disease in rats by modulating oxidative stress and inflammation
SY Du, YL Zhang, RX Bai, ZL Ai, BS Xie… - International journal of …, 2015 - ncbi.nlm.nih.gov
Objective: Oxidative stress and inflammation play an important role in pathogenesis of
alcohol-induced liver injury. The present study was designed to investigate the protective …
alcohol-induced liver injury. The present study was designed to investigate the protective …
Protective anti-inflammatory activity of tovophyllin A against acute lung injury and its potential cytotoxicity to epithelial lung and breast carcinomas
DS El-Agamy, GA Mohamed, N Ahmed… - …, 2020 - Springer
Tovophyllin A (TA) is a xanthone isolated from Garcinia mangostana L.(GM, Guttiferae)
pericarps that possesses various beneficial bioactivities. However, its protective effects on …
pericarps that possesses various beneficial bioactivities. However, its protective effects on …
Putative anti-inflammatory, antioxidant, and anti-apoptotic roles of the natural tissue guardian methyl palmitate against isoproterenol-induced myocardial injury in rats
AB Hamed, EM Mantawy, WM El-Bakly… - Future Journal of …, 2020 - Springer
Background Myocardial injury is considered as a worldwide main cause of morbidity and
mortality. The present study aimed to investigate the probable cardioprotective activity of the …
mortality. The present study aimed to investigate the probable cardioprotective activity of the …
Circular RNA circVAPA modulates macrophage pyroptosis in sepsis‐induced acute lung injury through targeting miR‐212‐3p/Sirt1/Nrf2/NLRP3 axis
Y Huang, J Lin, Z Wu, Y Li - International Journal of …, 2024 - Wiley Online Library
Sepsis‐induced acute lung injury (ALI) is an inflammatory condition involving the pyroptosis
of macrophages. This study investigated the role of circular RNA hsa_circ_0006990 …
of macrophages. This study investigated the role of circular RNA hsa_circ_0006990 …
[HTML][HTML] Protective effect of kaempferol glucoside against lipopolysaccharide-caused acute lung injury via targeting Nrf2/NF-κB/NLRP3/GSDMD: Integrating …
WH Abdulaal, UM Omar, M Zeyadi… - Saudi Pharmaceutical …, 2024 - Elsevier
The current study explored the protective potential of kaempferol 3-sophoroside-7-glucoside
(KSG) against acute lung injury (ALI). Pre-treatment with KSG effectively secured mice from …
(KSG) against acute lung injury (ALI). Pre-treatment with KSG effectively secured mice from …