Biological systems are composed of heterogeneous populations of cells that
intercommunicate to form a functional living tissue. Biological function varies greatly across …

This review focuses on the state of the art on neuropeptide receptors in insects. Most of
these receptors are G protein-coupled receptors (GPCRs) and are involved in the regulation …

Single-cell mass spectrometry (MS) empowers metabolomic investigations by decreasing
analytical dimensions to the size of individual cells and subcellular structures. We describe a …

Central pattern generators are subject to extensive modulation that generates flexibility in
the rhythmic outputs of these neural networks. The effects of neuromodulators interact with …

Single-cell analysis is gaining popularity in the field of mass spectrometry as a method for
analyzing protein and peptide content in cells. The spatial resolution of MALDI mass …

Neuropeptides are a diverse class of signalling molecules that are widely employed as
neurotransmitters and neuromodulators in animals, both invertebrate and vertebrate …

Measuring the chemical composition of individual cells in mammalian organs can provide
critical insights toward understanding the mechanisms leading to their normal and …

Imaging mass spectrometry is emerging as a powerful tool that has been applied extensively
for the localization of proteins, peptides, pharmaceutical compounds, metabolites, and lipids …

The function and activity of almost every circuit in the human brain are modified by the
signaling peptides (SPs) surrounding the neurons. As the complement of peptides can vary …

Metabolomics, the characterization of metabolites and their changes within biological
systems, has seen great technological and methodological progress over the past decade …