Intense genome sequencing of Pseudomonas aeruginosa isolates from cystic fibrosis (CF)
airways has shown inefficient eradication of the infecting bacteria, as well as previously …

Bacterial biofilms are communities of bacteria that exist as aggregates that can adhere to
surfaces or be free-standing. This complex, social mode of cellular organization is …

First proposed as antimicrobial agents, histones were later recognized for their role in
condensing chromosomes. Histone antimicrobial activity has been reported in innate …

In burn patients Pseudomonas aeruginosa infection is a major cause of morbidity. Analysis
of the pathogen's gene expression as it transitions from colonization to acute and then …

In light of the antibiotic crisis, emerging strategies to sensitize bacteria to available
antibiotics should be explored. Several studies on the mechanisms of killing suggest that …

Pf4 is a filamentous bacteriophage integrated as a prophage into the genome of
Pseudomonas aeruginosa PAO1. Pf4 virions can be produced without killing P. aeruginosa …

In the field of fluorescence microscopy, there is continued demand for dynamic technologies
that can exploit the complete information from every pixel of an image. One imaging …

In the face of growing antimicrobial resistance, there is an urgent need for the development
of effective strategies to target Pseudomonas aeruginosa. This metabolically versatile …

Nicotinamide adenine dinucleotide (NAD+) serves as a critical cofactor in cellular
metabolism and redox reactions. Bacterial pathways rely on NAD+ participation, where its …

Pseudomonas aeruginosa is a prime opportunistic pathogen, one of the most important
causes of hospital-acquired infections and the major cause of morbidity and mortality in …