Understanding extracellular vesicle diversity–current status

DW Greening, RJ Simpson - Expert review of proteomics, 2018 - Taylor & Francis
ABSTRACT Introduction: Extracellular vesicles (EVs) represent an important mode of
intercellular communication. There is now a growing awareness that predominant EV …

Systems and synthetic biology to elucidate secondary metabolite biosynthetic gene clusters encoded in Streptomyces genomes

N Lee, S Hwang, W Kim, Y Lee, JH Kim, S Cho… - Natural Product …, 2021 - pubs.rsc.org
Covering: 2010 to 2020 Over the last few decades, Streptomyces have been extensively
investigated for their ability to produce diverse bioactive secondary metabolites. Recent …

Carry-over effects of dry period heat stress on the mammary gland proteome and phosphoproteome in the subsequent lactation of dairy cows

AL Skibiel, J Koh, N Zhu, F Zhu, MJ Yoo, J Laporta - Scientific Reports, 2022 - nature.com
Exposure to heat stress during a cow's dry period disrupts mammary gland remodeling,
impairing mammary function and milk production during the subsequent lactation. Yet …

Integrative transcriptomics and proteomics profiling of Arabidopsis thaliana elucidates novel mechanisms underlying spaceflight adaptation

GO Olanrewaju, NJ Haveman, MJ Naldrett… - Frontiers in Plant …, 2023 - frontiersin.org
Spaceflight presents a unique environment with complex stressors, including microgravity
and radiation, that can influence plant physiology at molecular levels. Combining …

Recent advances in bacterial signaling by serine/threonine protein kinases

SN Nagarajan, C Lenoir, C Grangeasse - Trends in Microbiology, 2022 - cell.com
It has been nearly three decades since the discovery of the first bacterial serine/threonine
protein kinase (STPK). Since then, a blend of technological advances has led to the …

IreK-Mediated, Cell Wall-Protective Phosphorylation in Enterococcus faecalis

AA Iannetta, NE Minton, AA Uitenbroek… - Journal of proteome …, 2021 - ACS Publications
Enterococcus faecalis is a Gram-positive bacterium that is a major cause of hospital-
acquired infections due, in part, to its intrinsic resistance to cell wall-active antimicrobials …

Streptomyces as a source of antimicrobials: novel approaches to activate cryptic secondary metabolite pathways

Á Manteca, P Yagüe - Antimicrobials, Antibiotic Resistance …, 2019 - books.google.com
Streptomyces is the most important bacterial genus for bioactive compound production.
These soil bacteria are characterized by a complex differentiation cycle. Streptomyces is …

Regulation of protein post-translational modifications on metabolism of actinomycetes

CF Sun, YQ Li, XM Mao - Biomolecules, 2020 - mdpi.com
Protein post-translational modification (PTM) is a reversible process, which can dynamically
regulate the metabolic state of cells through regulation of protein structure, activity …

Clostridioides difficile phosphoproteomics shows an expansion of phosphorylated proteins in stationary growth phase

WK Smits, Y Mohammed, AH de Ru, V Cordo'… - Msphere, 2022 - Am Soc Microbiol
Phosphorylation is a posttranslational modification that can affect both housekeeping
functions and virulence characteristics in bacterial pathogens. In the Gram-positive …

Goals and challenges in bacterial phosphoproteomics

P Yagüe, N Gonzalez-Quiñonez… - International Journal of …, 2019 - mdpi.com
Reversible protein phosphorylation at serine, threonine and tyrosine is a well-known
dynamic post-translational modification with stunning regulatory and signalling functions in …