Integration of Circadian Clock Information in the Drosophila Circadian Neuronal Network

M Ahmad, W Li, D Top - Journal of Biological Rhythms, 2021 - journals.sagepub.com
Circadian clocks are biochemical time-keeping machines that synchronize animal behavior
and physiology with planetary rhythms. In Drosophila, the core components of the clock …

Integration of photoperiodic and temperature cues by the circadian clock to regulate insect seasonal adaptations

S Hidalgo, JC Chiu - Journal of Comparative Physiology A, 2024 - Springer
Organisms adapt to unfavorable seasonal conditions to survive. These seasonal
adaptations rely on the correct interpretation of environmental cues such as photoperiod …

Connectomic analysis of the Drosophila lateral neuron clock cells reveals the synaptic basis of functional pacemaker classes

OT Shafer, GJ Gutierrez, K Li, A Mildenhall, D Spira… - Elife, 2022 - elifesciences.org
The circadian clock orchestrates daily changes in physiology and behavior to ensure
internal temporal order and optimal timing across the day. In animals, a central brain clock …

The lateral posterior clock neurons of Drosophila melanogaster express three neuropeptides and have multiple connections within the circadian clock network and …

N Reinhard, E Bertolini, A Saito… - Journal of …, 2022 - Wiley Online Library
Drosophila's lateral posterior neurons (LPNs) belong to a small group of circadian clock
neurons that is so far not characterized in detail. Thanks to a new highly specific split‐Gal4 …

Daily rewiring of a neural circuit generates a predictive model of environmental light

BJ Song, SJ Sharp, D Rogulja - Science Advances, 2021 - science.org
Behavioral responsiveness to external stimulation is shaped by context. We studied how
sensory information can be contextualized, by examining light-evoked locomotor …

A subclass of evening cells promotes the switch from arousal to sleep at dusk

MP Brown, S Verma, I Palmer, AG Zuniga, A Mehta… - Current Biology, 2024 - cell.com
Animals exhibit rhythmic patterns of behavior that are shaped by an internal circadian clock
and the external environment. Although light intensity varies across the day, there are …

Alignment between glioblastoma internal clock and environmental cues ameliorates survival in Drosophila

P Jarabo, CG Barredo, C de Pablo… - Communications …, 2022 - nature.com
Virtually every single living organism on Earth shows a circadian (ie “approximately a day”)
internal rhythm that is coordinated with planet rotation (ie 24 hours). External cues …

The Drosophila circadian clock circuit is a nonhierarchical network of peptidergic oscillators

SL Crespo-Flores, AF Barber - Current Opinion in Insect Science, 2022 - Elsevier
The relatively simple Drosophila circadian clock circuit consists of 150 clock neurons that
coordinate rhythmic behavior and physiology, which are generally classified based on …

Conditional chemoconnectomics (cCCTomics) as a strategy for efficient and conditional targeting of chemical transmission

R Mao, J Yu, B Deng, X Dai, Y Du, S Du, W Zhang… - Elife, 2024 - elifesciences.org
Dissection of neural circuitry underlying behaviors is a central theme in neurobiology. We
have previously proposed the concept of chemoconnectome (CCT) to cover the entire …

Circadian plasticity evolves through regulatory changes in a neuropeptide gene

MP Shahandeh, L Abuin, L Lescuyer De Decker… - Nature, 2024 - nature.com
Many organisms, including cosmopolitan drosophilids, show circadian plasticity, varying
their activity with changing dawn–dusk intervals. How this behaviour evolves is unclear …