[HTML][HTML] In vitro Models of Neurodegenerative Diseases
A Slanzi, G Iannoto, B Rossi, E Zenaro… - Frontiers in cell and …, 2020 - frontiersin.org
Neurodegenerative diseases are progressive degenerative conditions characterized by the
functional deterioration and ultimate loss of neurons. These incurable and debilitating …
functional deterioration and ultimate loss of neurons. These incurable and debilitating …
The SH-SY5Y cell line: a valuable tool for Parkinson's disease drug discovery
Introduction Owing to limited efficient treatment strategies for highly prevalent and
distressing Parkinson's disease (PD), an impending need emerged for deciphering new …
distressing Parkinson's disease (PD), an impending need emerged for deciphering new …
Cannabidiol exerts protective effects in an in vitro model of Parkinson's disease activating AKT/mTOR pathway
A Gugliandolo, F Pollastro, P Bramanti, E Mazzon - Fitoterapia, 2020 - Elsevier
Parkinson's disease (PD) is a neurodegenerative disorder characterized by the
degeneration of the nigrostriatal dopaminergic pathway with loss of substantia nigra pars …
degeneration of the nigrostriatal dopaminergic pathway with loss of substantia nigra pars …
Lewy Body-like Pathology and Loss of Dopaminergic Neurons in Midbrain Organoids Derived from Familial Parkinson's Disease Patient
Progressive accumulation of α-Synuclein (αSyn) in Lewy bodies (LBs) and loss of
dopaminergic (DA) neurons are the hallmark pathological features of Parkinson's disease …
dopaminergic (DA) neurons are the hallmark pathological features of Parkinson's disease …
Multi-omics integration of scRNA-seq time series data predicts new intervention points for Parkinson's disease
Parkinson's disease (PD) is a complex neurodegenerative disorder without a cure. The
onset of PD symptoms corresponds to 50% loss of midbrain dopaminergic (mDA) neurons …
onset of PD symptoms corresponds to 50% loss of midbrain dopaminergic (mDA) neurons …
Parkinson's disease: exploring different animal model systems
Disease modeling in non-human subjects is an essential part of any clinical research. To
gain proper understanding of the etiology and pathophysiology of any disease, experimental …
gain proper understanding of the etiology and pathophysiology of any disease, experimental …
Retinal organoids from human-induced pluripotent stem cells: From studying retinal dystrophies to early diagnosis of Alzheimer's and Parkinson's disease
MI Móvio, TH de Lima-Vasconcellos… - Seminars in Cell & …, 2023 - Elsevier
Human-induced pluripotent stem cells (hiPSCs) have provided new methods to study
neurodegenerative diseases. In addition to their wide application in neuronal disorders …
neurodegenerative diseases. In addition to their wide application in neuronal disorders …
[HTML][HTML] An overall view of the most common experimental models for multiple sclerosis
S Dedoni, M Scherma, C Camoglio, C Siddi… - Neurobiology of …, 2023 - Elsevier
Multiple sclerosis (MS) is a complex chronic disease with an unknown etiology. It is
considered an inflammatory demyelinating and neurodegenerative disorder of the central …
considered an inflammatory demyelinating and neurodegenerative disorder of the central …
Back and to the future: from neurotoxin‐induced to human Parkinson's disease models
Parkinson's disease (PD) is an age‐related neurodegenerative disorder characterized by
motor symptoms such as tremor, slowness of movement, rigidity, and postural instability, as …
motor symptoms such as tremor, slowness of movement, rigidity, and postural instability, as …
[HTML][HTML] From cell lines to pluripotent stem cells for modelling Parkinson's Disease
Parkinson's disease (PD) is the second most common neurodegenerative disorder
characterized by loss of dopaminergic (DAergic) neurons in the substantia nigra (SN) that …
characterized by loss of dopaminergic (DAergic) neurons in the substantia nigra (SN) that …