Targeting ROS in cancer: rationale and strategies
C Glorieux, S Liu, D Trachootham… - Nature Reviews Drug …, 2024 - nature.com
Reactive oxygen species (ROS) in biological systems are transient but essential molecules
that are generated and eliminated by a complex set of delicately balanced molecular …
that are generated and eliminated by a complex set of delicately balanced molecular …
Recent advancements in the targeted delivery of etoposide nanomedicine for cancer therapy: A comprehensive review
Etoposide (ETO), a popular anticancer drug that inhibits topoisomerase II enzymes, may be
administered more effectively and efficiently due to nanomedicine. The therapeutic …
administered more effectively and efficiently due to nanomedicine. The therapeutic …
Recent insights into nanotechnology in colorectal cancer
AAZ Dezfuli, M Abu-Elghait, SS Salem - Applied Biochemistry and …, 2024 - Springer
Colorectal cancer (CRC) is the third cancer among the known causes of cancer that impact
people. Although CRC drug options are imperfect, primary detection of CRC can play a key …
people. Although CRC drug options are imperfect, primary detection of CRC can play a key …
Naturally and chemically acetylated polysaccharides: Structural characteristics, synthesis, activities, and applications in the delivery system: A review
H Li, Y Wang, P Zhao, L Guo, L Huang, X Li… - Carbohydrate Polymers, 2023 - Elsevier
Acetylated polysaccharides refer to polysaccharides containing acetyl groups on sugar
units. In the past, the acetylation modification of wall polysaccharides has been a hot …
units. In the past, the acetylation modification of wall polysaccharides has been a hot …
A review of chitosan in gene therapy: developments and challenges
L Dong, Y Li, H Cong, B Yu, Y Shen - Carbohydrate Polymers, 2024 - Elsevier
Gene therapy, as a revolutionary treatment, has been gaining more and more attention. The
key to gene therapy is the selection of suitable vectors for protection of exogenous nucleic …
key to gene therapy is the selection of suitable vectors for protection of exogenous nucleic …
Hyaluronic acid-based prodrug nanomedicines for enhanced tumor targeting and therapy: A review
R Zhang, X Zhao, A Jia, C Wang, H Jiang - International Journal of …, 2023 - Elsevier
Hyaluronic acid (HA) represents a natural polysaccharide which has attracted significant
attention owing to its improved tumor targeting capacity, enzyme degradation capacity, and …
attention owing to its improved tumor targeting capacity, enzyme degradation capacity, and …
Inhibition of iRhom1 by CD44-targeting nanocarrier for improved cancer immunochemotherapy
The multifaceted chemo-immune resistance is the principal barrier to achieving cure in
cancer patients. Identifying a target that is critically involved in chemo-immune-resistance …
cancer patients. Identifying a target that is critically involved in chemo-immune-resistance …
Nano-sized fucoidan interpolyelectrolyte complexes: Recent advances in design and prospects for biomedical applications
NV Dubashynskaya, ER Gasilova… - International Journal of …, 2023 - mdpi.com
The marine polysaccharide fucoidan (FUC) is a promising polymer for pharmaceutical
research and development of novel drug delivery systems with modified release and …
research and development of novel drug delivery systems with modified release and …
Green synthesis of hyaluronic acid coated, thiolated chitosan nanoparticles for CD44 targeted delivery and sustained release of Cisplatin in cervical carcinoma
Cervical carcinoma is one of the most prevalent gynecological cancers throughout the world.
Cisplatin is used as first line chemotherapy for treatment of cervical cancer, but it comes with …
Cisplatin is used as first line chemotherapy for treatment of cervical cancer, but it comes with …
Engineered mesoporous silica nanoparticles, new insight nanoplatforms into effective cancer gene therapy
R Heidari, V Assadollahi, P Khosravian… - International Journal of …, 2023 - Elsevier
The use of nucleic acid to control the expression of genes relevant to tumor progression is a
key therapeutic approach in cancer research. Therapeutics based on nucleic acid provide …
key therapeutic approach in cancer research. Therapeutics based on nucleic acid provide …