Leptospirosis: a neglected tropical zoonotic infection of public health importance—an updated review

KB Karpagam, B Ganesh - European Journal of Clinical Microbiology & …, 2020 - Springer
Leptospirosis is a zoonotic and waterborne disease worldwide. It is a neglected, reemerging
disease of global public health importance with respect to morbidity and mortality both in …

Virulence of the zoonotic agent of leptospirosis: still terra incognita?

M Picardeau - Nature Reviews Microbiology, 2017 - nature.com
Pathogenic leptospires are the bacterial agents of leptospirosis, which is an emerging
zoonotic disease that affects animals and humans worldwide. The success of leptospires as …

Spatiotemporal determinants of urban leptospirosis transmission: four-year prospective cohort study of slum residents in Brazil

JE Hagan, P Moraga, F Costa, N Capian… - PLoS neglected …, 2016 - journals.plos.org
Background Rat-borne leptospirosis is an emerging zoonotic disease in urban slum
settlements for which there are no adequate control measures. The challenge in elucidating …

Deciphering the unexplored Leptospira diversity from soils uncovers genomic evolution to virulence

R Thibeaux, G Iraola, I Ferrés, E Bierque… - Microbial …, 2018 - microbiologyresearch.org
Despite recent advances in our understanding of the genomics of members of the genus
Leptospira, little is known on how virulence has emerged in this heterogeneous bacterial …

Epidemiology of human leptospirosis in urban and rural areas of Brazil, 2000–2015

DI Galan, AA Roess, SVC Pereira, MC Schneider - PLoS One, 2021 - journals.plos.org
Background Leptospirosis is one of the most widespread zoonosis in the world and Brazil
has the highest number of cases in Latin America. Transmission occurs mainly through …

Diversity of infectious aetiologies of acute undifferentiated febrile illnesses in south and Southeast Asia: a systematic review

K Wangdi, K Kasturiaratchi, SV Nery, CL Lau… - BMC infectious …, 2019 - Springer
Background Acute undifferentiated febrile illness (AUFI) is caused by a multitude of diverse
pathogens, with significant morbidity and mortality in the developing world. The objective of …

Risk factors for human leptospirosis following flooding: A meta-analysis of observational studies

C Naing, SA Reid, SN Aye, NH Htet, S Ambu - PloS one, 2019 - journals.plos.org
Leptospirosis is probably the most widespread zoonotic disease in the world especially in
tropical countries. There has been an increase in individual studies, which assessed the …

A systematic review of human and animal leptospirosis in the Pacific Islands reveals pathogen and reservoir diversity

V Guernier, C Goarant, J Benschop… - PLoS neglected tropical …, 2018 - journals.plos.org
Background The Pacific Islands have environmental conditions highly favourable for
transmission of leptospirosis, a neglected zoonosis with highest incidence in the tropics, and …

Demographic and clinical risk factors associated with severity of lab-confirmed human leptospirosis in Colombia, 2015–2020

EL Parra Barrera, S Bello Piruccini… - PLoS Neglected …, 2023 - journals.plos.org
Background Leptospirosis is a common zoonoses and is a major global public health threat.
Most cases are mild, typically presenting as a non-specific acute febrile illness. However …

Leptospirosis renal disease: emerging culprit of chronic kidney disease unknown etiology

CW Yang - Nephron, 2018 - karger.com
Leptospirosis is the most prevalent zoonosis affecting more than 1 million populations
worldwide. Interestingly, leptospirosis endemic regions coincide with chronic kidney disease …