Self-assembling peptide and protein amyloids: from structure to tailored function in nanotechnology
Self-assembled peptide and protein amyloid nanostructures have traditionally been
considered only as pathological aggregates implicated in human neurodegenerative …
considered only as pathological aggregates implicated in human neurodegenerative …
Nano-biosensors to detect beta-amyloid for Alzheimer's disease management
Abstract Beta-amyloid (β-A) peptides are potential biomarkers to monitor Alzheimer's
diseases (AD) for diagnostic purposes. Increased β-A level is neurotoxic and induces …
diseases (AD) for diagnostic purposes. Increased β-A level is neurotoxic and induces …
Cell-membrane-mimicking lipid-coated nanoparticles confer Raman enhancement to membrane proteins and reveal membrane-attached amyloid-β conformation
Identifying the structures of membrane bound proteins is critical to understanding their
function in healthy and diseased states. We introduce a surface enhanced Raman …
function in healthy and diseased states. We introduce a surface enhanced Raman …
Amyloid‐Mediated Fabrication of Organic–Inorganic Hybrid Materials and Their Biomedical Applications
J Zhao, P Yang - Advanced Materials Interfaces, 2020 - Wiley Online Library
Protein assembly with ordered architecture plays an important role in the formation of natural
organic–inorganic hybrid materials, and also determines their distinguished mechanical …
organic–inorganic hybrid materials, and also determines their distinguished mechanical …
Detection and modulation of neurodegenerative processes using graphene-based nanomaterials: Nanoarchitectonics and applications
Neurodegenerative disorders (NDDs) are caused by progressive loss of functional neurons
following the aggregation and fibrillation of proteins in the central nervous system. The …
following the aggregation and fibrillation of proteins in the central nervous system. The …
Hydrostatic pressure increases the catalytic activity of amyloid fibril enzymes
TQ Luong, N Erwin, M Neumann… - Angewandte Chemie …, 2016 - Wiley Online Library
We studied the combined effects of pressure (0.1–200 MPa) and temperature (22, 30, and
38° C) on the catalytic activity of designed amyloid fibrils using a high‐pressure stopped …
38° C) on the catalytic activity of designed amyloid fibrils using a high‐pressure stopped …
Self‐assembly in protein‐based bionanomaterials
A Solomonov, U Shimanovich - Israel Journal of Chemistry, 2020 - Wiley Online Library
Supramolecular self‐assembled structures, based on protein− protein interactions, have
garnered widespread interest as prospective functional bionanomaterials. Possessing …
garnered widespread interest as prospective functional bionanomaterials. Possessing …
Ethanol controls the self-assembly and mesoscopic properties of human insulin amyloid spherulites
Protein self-assembly into amyloid fibrils or highly hierarchical superstructures is closely
linked to neurodegenerative pathologies as Alzheimer's and Parkinson's diseases …
linked to neurodegenerative pathologies as Alzheimer's and Parkinson's diseases …
[HTML][HTML] An atomistic view of amyloidogenic self-assembly: structure and dynamics of heterogeneous conformational states in the pre-nucleation phase
The formation of well-defined filamentous amyloid structures involves a polydisperse
collection of oligomeric states for which relatively little is known in terms of structural …
collection of oligomeric states for which relatively little is known in terms of structural …
Genetically-tunable mechanical properties of bacterial functional amyloid nanofibers
Bacterial biofilms are highly ordered, complex, dynamic material systems including cells,
carbohydrates, and proteins. They are known to be resistant against chemical, physical, and …
carbohydrates, and proteins. They are known to be resistant against chemical, physical, and …