Arterial hypertension in women: state of the art and knowledge gaps

N Chapman, SM Ching, AO Konradi, AM Nuyt… - …, 2023 - Am Heart Assoc
Hypertension is the leading risk factor for cardiovascular disease and premature death
among women globally. However, there is a fundamental lack of knowledge regarding the …

[PDF][PDF] Systemic discrimination: Theory and measurement

JA Bohren, P Hull, A Imas - 2022 - aeaweb.org
Disparities by race, gender, and other protected characteristics have been widely
documented in many important settings—such as employment, housing, criminal justice …

Diversity in randomized clinical trials for peripheral artery disease: a systematic review

C Long, AO Williams, AM McGovern… - International journal for …, 2024 - Springer
Background Significant race and sex disparities exist in the prevalence, diagnosis, and
outcomes of peripheral artery disease (PAD). However, clinical trials evaluating treatments …

Are sex and gender considered in head and neck cancer clinical studies?

A Gaeta, M Tagliabue, O D'Ecclesiis, L Ghiani… - NPJ Precision …, 2023 - nature.com
We analyzed the inclusion of sex and/or gender (S/G) in Head and Neck Cancer (HNC)
clinical studies, through inspecting ClinicalTrials. gov (AACT) and the mention of Human …

The importance of including both sexes in preclinical sleep studies and analyses

GS Mannino, TRF Green, SM Murphy, KD Donohue… - Scientific Reports, 2024 - nature.com
A significant effort in biomedical sciences has been made to examine relationships between
sex and the mechanisms underlying various disease states and behaviors, including sleep …

[HTML][HTML] Representation of women in contemporary kidney transplant trials

AJ Vinson, SB Ahmed - Transplant International, 2023 - frontierspartnerships.org
Women are often underrepresented in clinical trials. It is unclear if this applies to trials in
kidney transplant (KT) and whether the intervention or trial focus influences this. In this study …

Sex-specific differences in risk factors, comorbidities, diagnostic challenges, optimal management, and prognostic outcomes of heart failure with preserved ejection …

M Abubakar, A Saleem, M Hajjaj, H Faiz, A Pragya… - Heart failure …, 2024 - Springer
Due to hormonal variations, heart failure with preserved ejection fraction (HFpEF) remains
prevalent in women and affects almost half of the heart failure (HF) patients. Given the yearly …

Genetic context drives age‐related disparities in synaptic maintenance and structure across cortical and hippocampal neuronal circuits

SE Heuer, EW Nickerson, GR Howell, EB Bloss - Aging cell, 2024 - Wiley Online Library
The disconnection of neuronal circuitry through synaptic loss is presumed to be a major
driver of age‐related cognitive decline. Age‐related cognitive decline is heterogeneous, yet …

Raising awareness of sex and gender bias in artificial intelligence and health

N Buslón, A Cortés, S Catuara-Solarz… - Frontiers in Global …, 2023 - frontiersin.org
Historically, biomedical research has been led by and focused on men. The recent
introduction of Artificial Intelligence (AI) in this area has further proven this practice to be …

Risk Factors and Cellular Differences in Heart Failure: The Key Role of Sex Hormones

E Delcuratolo, A Palazzuoli, F Coppi, AV Mattioli… - Biomedicines, 2023 - mdpi.com
Patients with heart failure are conventionally stratified into phenotypic groups based on their
ejection fraction. The aim of this stratification is to improve disease management with a more …