Genetics of acute rejection after kidney transplantation

CR Dorr, WS Oetting, PA Jacobson… - Transplant …, 2018 - Wiley Online Library
Treatment of acute rejection (AR) following kidney transplantation has improved in recent
years, but there are still limitations to successful outcomes. This review article covers …

Serum and urinary biomarkers in acute kidney transplant rejection

N Alachkar - Nephrologie & therapeutique, 2012 - Elsevier
BACKGROUND: Acute rejection (AR) is a common medical problem among kidney
transplant recipients, which may cause a significant impact on patients' and allografts' …

[HTML][HTML] The role of endothelins, IL-18, and NGAL in kidney hypothermic machine perfusion

K Tejchman, A Nowacki, K Kotfis, E Skwirczynska… - Biomedicines, 2021 - mdpi.com
Ischemia-reperfusion injury (IRI) occurring after renal transplantation is a complex
biochemical process that can be monitored by specific biomarkers. The roles of those are …

Genetic predictors of acute renal transplant rejection

AS Goldfarb-Rumyantzev… - Nephrology Dialysis …, 2010 - academic.oup.com
While rates of acute rejection (AR) continue to decrease, it remains the strongest predictor of
long-term allograft survival [1–5]. Better understanding of factors predicting AR may …

Analysis of 75 candidate SNPs associated with acute rejection in kidney transplant recipients: validation of rs2910164 in microRNA MIR146A

WS Oetting, DP Schladt, CR Dorr, B Wu, W Guan… - …, 2019 - journals.lww.com
Background. Identifying kidney allograft recipients who are predisposed to acute rejection
(AR) could allow for optimization of clinical treatment to avoid rejection and prolong graft …

Validation of single nucleotide polymorphisms associated with acute rejection in kidney transplant recipients using a large multi‐center cohort

WS Oetting, DP Schladt, RE Leduc… - Transplant …, 2011 - Wiley Online Library
There have been numerous reports proposing a statistically significant association between
a genetic variant, usually in the form of a single nucleotide polymorphism (SNP), and acute …

Genetic polymorphisms in the immune response: A focus on kidney transplantation

J Stojanova, L Pouché, N Picard - Clinical Biochemistry, 2016 - Elsevier
The modulation of the immune system following solid organ transplantation has made
considerable progress with new immunosuppressive regimens and has considerably …

Study of the cytokine polymorphisms in correlation to rejection and graft survival in renal allograft donors and recipients from a homogenous Saudi population

A Gaafar, A Iqniebi, A Sheereen, A Eldali… - Transplant …, 2014 - Elsevier
Objectives Allograft outcome can be improved with the discovery of risk factors that influence
adverse events and may allow individualization of patients' treatment. Rejection is the main …

The relationship between interferon‐γ gene polymorphism and acute kidney allograft rejection

L Zibar, J Wagner, D Pavlinić, J Galić… - Scandinavian …, 2011 - Wiley Online Library
Cytokine gene polymorphisms have been associated with modified gene expression and
cytokine production. Gamma interferon (IFN‐γ) plays an important role in the pathogenesis …

Interleukin 18-607 a/c gene polymorphism is associated with susceptibility to iga nephropathy in a chinese han population

B Yang, W Feng, Y Li, Y Shi, B Cai, Y Liao… - Applied …, 2017 - journals.lww.com
The association between a single-nucleotide polymorphism (SNP;-607A/C) in the promoter
region of the IL-18 gene with IL-18 promoter transcription activity and the level of IL-18 …