The neuromuscular junction in health and disease: molecular mechanisms governing synaptic formation and homeostasis
PM Rodríguez Cruz, J Cossins, D Beeson… - Frontiers in molecular …, 2020 - frontiersin.org
The neuromuscular junction (NMJ) is a highly specialized synapse between a motor neuron
nerve terminal and its muscle fiber that are responsible for converting electrical impulses …
nerve terminal and its muscle fiber that are responsible for converting electrical impulses …
Neuromuscular junction formation, aging, and disorders
Synapses, the fundamental unit in neuronal circuits, are critical for learning and memory,
perception, thinking, and reaction. The neuromuscular junction (NMJ) is a synapse formed …
perception, thinking, and reaction. The neuromuscular junction (NMJ) is a synapse formed …
To build a synapse: signaling pathways in neuromuscular junction assembly
Synapses, as fundamental units of the neural circuitry, enable complex behaviors. The
neuromuscular junction (NMJ) is a synapse type that forms between motoneurons and …
neuromuscular junction (NMJ) is a synapse type that forms between motoneurons and …
Control of synapse development and plasticity by Rho GTPase regulatory proteins
Synapses are specialized cell–cell contacts that mediate communication between neurons.
Most excitatory synapses in the brain are housed on dendritic spines, small actin-rich …
Most excitatory synapses in the brain are housed on dendritic spines, small actin-rich …
Molecular mechanisms underlying maturation and maintenance of the vertebrate neuromuscular junction
The vertebrate neuromuscular junction (NMJ), a peripheral synapse formed between
motoneuron and skeletal muscle, is characterized by a protracted postnatal period of …
motoneuron and skeletal muscle, is characterized by a protracted postnatal period of …
Homeostatic plasticity at the Drosophila neuromuscular junction
CA Frank - Neuropharmacology, 2014 - Elsevier
In biology, homeostasis refers to how cells maintain appropriate levels of activity. This
concept underlies a balancing act in the nervous system. Synapses require flexibility (ie …
concept underlies a balancing act in the nervous system. Synapses require flexibility (ie …
Interactions between EGFR and EphA2 promote tumorigenesis through the action of Ephexin1
J Kim, IY Chang, HJ You - Cell Death & Disease, 2022 - nature.com
The cell signaling factors EGFR, EphA2, and Ephexin1 are associated with lung and
colorectal cancer and play an important role in tumorigenesis. Although the respective …
colorectal cancer and play an important role in tumorigenesis. Although the respective …
Secreted signaling molecules at the neuromuscular junction in physiology and pathology
Signal transduction at the neuromuscular junction (NMJ) is affected in many human
diseases, including congenital myasthenic syndromes (CMS), myasthenia gravis, Lambert …
diseases, including congenital myasthenic syndromes (CMS), myasthenia gravis, Lambert …
[HTML][HTML] Human motor endplate remodeling after traumatic nerve injury
R Gupta, JP Chan, J Uong, WA Palispis… - Journal of …, 2020 - thejns.org
OBJECTIVE Current management of traumatic peripheral nerve injuries is variable with
operative decisions based on assumptions that irreversible degeneration of the human …
operative decisions based on assumptions that irreversible degeneration of the human …
Role of nucleosome remodeling in neurodevelopmental and intellectual disability disorders
It is becoming increasingly important to understand how epigenetic mechanisms control
gene expression during neurodevelopment. Two epigenetic mechanisms that have received …
gene expression during neurodevelopment. Two epigenetic mechanisms that have received …