Role of branched-chain amino acid metabolism in the pathogenesis of obesity and type 2 diabetes-related metabolic disturbances BCAA metabolism in type 2 …

F Vanweert, P Schrauwen, E Phielix - Nutrition & diabetes, 2022 - nature.com
Branched-chain amino acid (BCAA) catabolism has been considered to have an emerging
role in the pathogenesis of metabolic disturbances in obesity and type 2 diabetes (T2D) …

Deliberate practice and proposed limits on the effects of practice on the acquisition of expert performance: Why the original definition matters and recommendations for …

KA Ericsson, KW Harwell - Frontiers in psychology, 2019 - frontiersin.org
Over 25 years ago published the results of their search for the most effective forms of training
in music, a domain where knowledge of effective training has been accumulated over …

Transcriptomic profiling of skeletal muscle adaptations to exercise and inactivity

NJ Pillon, BM Gabriel, L Dollet, JAB Smith… - Nature …, 2020 - nature.com
The molecular mechanisms underlying the response to exercise and inactivity are not fully
understood. We propose an innovative approach to profile the skeletal muscle transcriptome …

Branched-chain amino acids in metabolic signalling and insulin resistance

CJ Lynch, SH Adams - Nature Reviews Endocrinology, 2014 - nature.com
Branched-chain amino acids (BCAAs) are important nutrient signals that have direct and
indirect effects. Frequently, BCAAs have been reported to mediate antiobesity effects …

Comprehensive analysis of lipids in biological systems by liquid chromatography-mass spectrometry

T Cajka, O Fiehn - TrAC Trends in Analytical Chemistry, 2014 - Elsevier
Liquid chromatography-mass spectrometry (LC-MS)-based lipidomics has undergone
dramatic developments over the past decade. This review focuses on state of the art in LC …

[HTML][HTML] β-Aminoisobutyric acid induces browning of white fat and hepatic β-oxidation and is inversely correlated with cardiometabolic risk factors

LD Roberts, P Boström, JF O'Sullivan, RT Schinzel… - Cell metabolism, 2014 - cell.com
The transcriptional coactivator peroxisome proliferator-activated receptor-gamma coactivator-
1α (PGC-1α) regulates metabolic genes in skeletal muscle and contributes to the response …

Towards a science of the acquisition of expert performance in sports: Clarifying the differences between deliberate practice and other types of practice

KA Ericsson - Journal of sports sciences, 2020 - Taylor & Francis
ABSTRACT Ericsson, Krampe, and Tesch-Römer published their research on “The role of
deliberate practice in the acquisition of expert performance” over 25 years ago. Since then …

[HTML][HTML] Physical activity and exercise in the regulation of human adipose tissue physiology

D Thompson, F Karpe, M Lafontan… - Physiological …, 2012 - journals.physiology.org
Physical activity and exercise are key components of energy expenditure and therefore of
energy balance. Changes in energy balance alter fat mass. It is therefore reasonable to ask …

Long-term leisure-time physical activity and serum metabolome

UM Kujala, VP Mäkinen, I Heinonen, P Soininen… - Circulation, 2013 - Am Heart Assoc
Background—Long-term physical inactivity seems to cause many health problems. We
studied whether persistent physical activity compared with inactivity has a global effect on …

Role of exercise in the activation of brown adipose tissue

G Sanchez-Delgado, B Martinez-Tellez… - Annals of Nutrition and …, 2015 - karger.com
Background: The energy-burning capacity of brown adipose tissue (BAT) makes it an
attractive target for use in anti-obesity therapies. Moreover, due to its ability to oxidize …