The language of genes
DB Searls - Nature, 2002 - nature.com
Linguistic metaphors have been woven into the fabric of molecular biology since its
inception. The determination of the human genome sequence has brought these metaphors …
inception. The determination of the human genome sequence has brought these metaphors …
[图书][B] Biological sequence analysis: probabilistic models of proteins and nucleic acids
Probabilistic models are becoming increasingly important in analysing the huge amount of
data being produced by large-scale DNA-sequencing efforts such as the Human Genome …
data being produced by large-scale DNA-sequencing efforts such as the Human Genome …
A dynamic programming algorithm for RNA structure prediction including pseudoknots
We describe a dynamic programming algorithm for predicting optimal RNA secondary
structure, including pseudoknots. The algorithm has a worst case complexity of O (N6) in …
structure, including pseudoknots. The algorithm has a worst case complexity of O (N6) in …
RNA pseudoknot prediction in energy-based models
RB Lyngsø, CNS Pedersen - Journal of computational biology, 2000 - liebertpub.com
RNA molecules are sequences of nucleotides that serve as more than mere intermediaries
between DNA and proteins, eg, as catalytic molecules. Computational prediction of RNA …
between DNA and proteins, eg, as catalytic molecules. Computational prediction of RNA …
[HTML][HTML] Dynamic programming algorithms for RNA secondary structure prediction with pseudoknots
T Akutsu - Discrete Applied Mathematics, 2000 - Elsevier
This paper shows simple dynamic programming algorithms for RNA secondary structure
prediction with pseudoknots. For a basic version of the problem (ie, maximizing the number …
prediction with pseudoknots. For a basic version of the problem (ie, maximizing the number …
Computational methods in noncoding RNA research
A Machado-Lima, HA Del Portillo… - Journal of mathematical …, 2008 - Springer
Non protein-coding RNAs (ncRNAs) are a research hotspot in bioinformatics. Recent
discoveries have revealed new ncRNA families performing a variety of roles, from gene …
discoveries have revealed new ncRNA families performing a variety of roles, from gene …
The language of RNA: a formal grammar that includes pseudoknots
Motivation: In a previous paper, we presented a polynomial time dynamic programming
algorithm for predicting optimal RNA secondary structure including pseudoknots. However …
algorithm for predicting optimal RNA secondary structure including pseudoknots. However …
Tree adjoining grammars for RNA structure prediction
Y Uemura, A Hasegawa, S Kobayashi… - Theoretical computer …, 1999 - Elsevier
In this paper, we are concerned with identifying a subclass of tree adjoining grammars
(TAGs) that is suitable for the application to modeling and predicting RNA secondary …
(TAGs) that is suitable for the application to modeling and predicting RNA secondary …
[图书][B] Algorithms in bioinformatics: A practical introduction
WK Sung - 2009 - taylorfrancis.com
Thoroughly Describes Biological Applications, Computational Problems, and Various
Algorithmic Solutions Developed from the author's own teaching material, Algorithms in …
Algorithmic Solutions Developed from the author's own teaching material, Algorithms in …
[HTML][HTML] Accelerated probabilistic inference of RNA structure evolution
I Holmes - BMC bioinformatics, 2005 - Springer
Background Pairwise stochastic context-free grammars (Pair SCFGs) are powerful tools for
evolutionary analysis of RNA, including simultaneous RNA sequence alignment and …
evolutionary analysis of RNA, including simultaneous RNA sequence alignment and …