Fine-tuning cellular physiology in response to intracellular and environmental cues requires
precise temporal and spatial control of gene expression. High-resolution imaging …

An RNA-based fluorogenic module consists of a light-up RNA aptamer able to specifically
interact with a fluorogen to form a fluorescent complex. Over the past decade, significant …

Despite the development of several cultivation methods, the rate of discovery of
microorganisms that are yet-to-be cultivated outpaces the rate of isolating and cultivating …

The first report of trans-acting RNA-based regulation in bacterial cells dates back to 1984.
Subsequent studies in diverse bacteria unraveled shared properties of trans-acting small …

Antimicrobial peptides (AMPs) are a promising alternative to classical antibiotics in the fight
against multi-resistant bacteria. They are produced by organisms from all domains of life and …

The E. coli transcriptome at the cell's poles (polar transcriptome) is unique compared to the
membrane and cytosol. Several factors have been suggested to mediate mRNA localization …

Only recently has it been recognized that the transcriptome of bacteria and archaea can be
spatiotemporally regulated. All types of prokaryotic transcripts—rRNAs, tRNAs, mRNAs, and …

Diverse mechanisms and functions of posttranscriptional regulation by small regulatory
RNAs and RNA-binding proteins have been described in bacteria. In contrast, little is known …

Microbes thrive in diverse habitats. They often form ecological niches with rich species
diversity and complex spatial structure. These communities drive biogeochemical cycles in …

Single-molecule fluorescence microscopy studies of bacteria provide unique insights into
the mechanisms of cellular processes and protein machineries in ways that are unrivalled by …