Role of polyanhydrides as localized drug carriers

JP Jain, S Modi, AJ Domb, N Kumar - Journal of Controlled Release, 2005 - Elsevier
Many drugs that are administered in an unmodified form by conventional systemic routes fail
to reach target organs in an effective concentration, or are not effective over a length of time …

Cyclic anhydrides as powerful tools for bioconjugation and smart delivery

MV Spanedda, L Bourel-Bonnet - Bioconjugate Chemistry, 2021 - ACS Publications
Cyclic anhydrides are potent tools for bioconjugation; therefore, they are broadly used in the
functionalization of biomolecules and carriers. The pH-dependent stability and reactivity, as …

In situ preparation of protein−“smart” polymer conjugates with retention of bioactivity

KL Heredia, D Bontempo, T Ly, JT Byers… - Journal of the …, 2005 - ACS Publications
Protein− polymer conjugates are widely used in biotechnology and medicine, and new
methods to prepare the bioconjugates would be advantageous for these applications. In this …

Diazonium− protein adducts for graphite electrode microarrays modification: direct and addressed electrochemical immobilization

BP Corgier, CA Marquette, LJ Blum - Journal of the American …, 2005 - ACS Publications
Diazonium cation electrodeposition was investigated for the direct and electro-addressed
immobilization of proteins. For the first time, this reaction was triggered directly onto …

Thermoresponsive Block Copolymer–Protein Conjugates Prepared by Grafting‐from via RAFT Polymerization

M Li, H Li, P De, BS Sumerlin - Macromolecular Rapid …, 2011 - Wiley Online Library
Well‐defined “smart” block copolymer–protein conjugates were prepared by two
consecutive “grafting‐from” reactions via reversible addition–fragmentation chain transfer …

Coadsorption of HIV-1 p24 and gp120 proteins to surfactant-free anionic PLA nanoparticles preserves antigenicity and immunogenicity

D Lamalle-Bernard, S Munier, C Compagnon… - Journal of controlled …, 2006 - Elsevier
Biodegradable micro-or nanoparticles with surface adsorbed antigens represent a
promising method for in vivo delivery of vaccines. Most vaccines, licensed or under …

Curious Binding Energy Increase between the Receptor-Binding Domain of the SARS-CoV-2 Spike Protein and Angiotensin-Converting Enzyme 2 Adsorbed on a …

S Lecot, Y Chevolot, M Phaner-Goutorbe… - The Journal of …, 2021 - ACS Publications
In the context of the COVID-19 outbreak since December 2019, antigenic tests are widely
used, for diagnosis purposes, to detect the SARS-CoV-2 spike protein in nasopharyngeal …

Engineering of Aerococcus viridansl-Lactate Oxidase for Site-Specific PEGylation: Characterization and Selective Bioorthogonal Modification of a S218C Mutant

B Unterweger, T Stoisser, S Leitgeb… - Bioconjugate …, 2012 - ACS Publications
A defined bioconjugate of Aerococcus viridans l-lactate oxidase and poly (ethylene glycol)
5000 was prepared and characterized in its structural and functional properties in …

One-step preparation of surface modified electrospun microfibers as suitable supports for protein immobilization

G Martrou, M Léonetti, D Gigmes, T Trimaille - Polymer Chemistry, 2017 - pubs.rsc.org
We have here developed a straightforward one-step route to surface modified polystyrene
(PS) based microfibers for protein/enzyme immobilization. Our approach consists of wet …

Macro-molecular chemiluminescent complex for enhanced immuno-detection onto microtiter plate and protein biochip

CA Marquette, P Hezard, A Degiuli, LJ Blum - Sensors and Actuators B …, 2006 - Elsevier
The synthesis and the analytical use of chemiluminescent (CL) macromolecular complexes
were studied. Such complexes, composed of dextran bearing both biotin and amine …