Aquaporins (AQPs) are ubiquitous membrane proteins whose identification, pioneered by
Peter Agre's team in the early nineties, provided a molecular basis for transmembrane water …

Background All thirteen known mammalian aquaporins have been detected in the eye.
Moreover, aquaporins have been identified as playing essential roles in ocular functions …

Congenital cataracts are a major cause of induced blindness in children, and inherited
cataracts are the major cause of congenital cataracts. Inherited congenital cataracts have …

Cataract and presbyopia are the leading cause of vision loss and impaired vision,
respectively, worldwide. Changes in lens biochemistry and physiology with age are …

Aquaporins (AQPs) constitute a major conduit for movement of water across plasma
membranes. AQP0 is expressed in the fiber cells and is critical for lens transparency and …

Aquaporins (AQPs) are a family of membrane water channel proteins that control osmotically-
driven water transport across cell membranes. Recent studies have focused on the …

Aquaporin 0 (AQP0) was originally characterized as a membrane intrinsic protein,
specifically expressed in the lens fibers of the ocular lens and designated MIP, for major …

Aquaporins (AQPs), by playing essential roles in the maintenance of ocular lens
homeostasis, contribute to the establishment and maintenance of the overall optical …

Aquaporins (AQPs) are a highly conserved group of membrane proteins that play critical
roles in water and small solute transport across epithelial and endothelial barriers. The aim …

α-crystallin is a major protein found in the mammalian eye lens that works as a molecular
chaperone by preventing the aggregation of proteins and providing tolerance to stress in the …