Methane, the predominant element in natural gas and biogas, represents a promising
alternative to carbon feedstocks in the biotechnological industry due to its low cost and high …

Industrial biotechnology can lead to new routes and potentially to more sustainable
production of numerous chemicals. We review the potential of biobased routes from sugars …

Metalloproteinase inhibitors often feature hydroxamate moieties to facilitate the chelation of
metal ions in the catalytic center of target enzymes. Actinonin and matlystatins are potent …

The biotechnological production of the methyl methacrylate precursor 2-hydroxyisobutyric
acid (2-HIBA) via bacterial poly-3-hydroxybutyrate (PHB) overflow metabolism requires …

Mycolicibacterium gadium IBE100 and Mycobacterium paragordonae IBE200 are aerobic,
chemoorganoheterotrophic bacteria isolated from activated sludge from a wastewater …

Cobamides, a uniquely diverse family of enzyme cofactors related to vitamin B12, are
produced exclusively by bacteria and archaea but used in all domains of life. While it is …

The crystal structures of the B12‐dependent isomerases (eliminating) diol dehydratase and
ethanolamine ammonia‐lyase complexed with adenosylcobalamin were solved with and …

Certain proteins utilize the high reactivity of radicals for catalysing chemically challenging
reactions. These proteins contain or form a radical and therefore named 'radical enzymes' …

Actinobacterial 2-hydroxyacyl-CoA lyase reversibly catalyzes the thiamine diphosphate-
dependent cleavage of 2-hydroxyisobutyryl-CoA to formyl-CoA and acetone. This enzyme …

Adenosylcobalamin (AdoCbl), or coenzyme B12, is a naturally occurring organometallic
compound that serves as a cofactor for enzymes that catalyze intramolecular group‐transfer …