TMT-based proteomics analysis reveals the protective effects of Xuefu Zhuyu decoction in a rat model of traumatic brain injury

D Zhou, J Liu, Y Hang, T Li, P Li, S Guo, T Liu… - Journal of …, 2020 - Elsevier
Abstract Ethnopharmacological relevance Xuefu Zhuyu decoction (XFZYD) is a traditional
Chinese herbal prescription. It is effective in treating traumatic brain injury (TBI). However …

Sighting acute myocardial infarction through platelet gene expression

G Gobbi, C Carubbi, GM Tagliazucchi, E Masselli… - Scientific reports, 2019 - nature.com
Acute myocardial infarction is primarily due to coronary atherosclerotic plaque rupture and
subsequent thrombus formation. Platelets play a key role in the genesis and progression of …

Platelet response to aspirin in UK and Irish pregnancy cohorts: a genome-wide approach

F Mone, JK Gupta, MM Phelan, S Meher, LY Lian… - Platelets, 2022 - Taylor & Francis
A multi-center prospective cross-sectional and genome-wide association study (GWAS)
recruited pregnant women taking low dose aspirin. Objectives were to (i) develop pregnancy …

MRP4 over-expression has a role on both reducing nitric oxide-dependent antiplatelet effect and enhancing ADP induced platelet activation

ML Guarino, I Massimi, L Alemanno, L Conti… - Journal of Thrombosis …, 2021 - Springer
The impact of inhibition of multidrug resistance protein 4 (MRP4) on nitric oxide (NO)
resistance and on ADP-induced platelet aggregation is unknown. The aim of this …

[PDF][PDF] Let us know how access to this document benefits yo u

G Gobbi, C Carubbi, GM Tagliazucchi, E Masselli… - core.ac.uk
Results The gene that showed the strongest evidence of differential expression between the
ST-segment elevation myocardial infarction (STEMI) and healthy donors (HD) groups (Table …

MRP4 (ABCC4) plaquettaire: rôle dans la compartimentation de l'AMPc et dans la pharmacologie de l'aspirine

A Leuci - 2020 - theses.hal.science
Les plaquettes sanguines circulent dans le sang au repos, cet état inactivé étant maintenu
par la production de prostacycline et de monoxyde d'azote par l'endothélium vasculaire. Ces …