Background Cytokine storm is the exaggerated immune response often observed in viral
infections. It is also intimately linked with the progression of COVID-19 disease as well as …

Abstract Novel coronavirus disease 2019 (COVID‐19) poses a global threat, due to its
fluctuating frequency and lethality. Published data revealed associations of COVID‐19 …

The recent global COVID-19 public health emergency is caused by SARS-CoV-2 infections
and can manifest extremely variable clinical symptoms. Host human genetic variability could …

Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) has been responsible for
the recent pandemic since early 2020. Due to the wide range of clinical symptoms of this …

The transmembrane serine protease 2 (TMPRSS2) is the major host protease that enables
entry of the severe acute respiratory syndrome coronavirus type 2 (SARS-CoV-2) into host …

Background: The human protein transmembrane protease serine type 2 (TMPRSS2) plays a
key role in SARS-CoV-2 infection, as it is required to activate the virus' spike protein …

Type II transmembrane serine proteases (TTSPs) are a family of trypsin-like membrane-
anchored serine proteases that play key roles in the regulation of some crucial processes in …

Methods: The study population consisted of the Ukrainian population with COVID-19:
patients without oxygen therapy (n= 62), with non-invasive (n= 92) and invasive (n= 35) …

SARS-CoV-2 uses the ACE2 receptor and the cellular protease TMPRSS2 for entry into
target cells. The present study aimed to establish if the TMPRSS2 polymorphisms are …

Single nucleotide polymorphisms (SNPs) are the most abundant type of genomic variation
and the most accessible to genotype in large cohorts. However, they individually explain a …