COVID-19, cytokines, inflammation, and spices: How are they related?
Background Cytokine storm is the exaggerated immune response often observed in viral
infections. It is also intimately linked with the progression of COVID-19 disease as well as …
infections. It is also intimately linked with the progression of COVID-19 disease as well as …
Genetic polymorphisms of ACE1, ACE2, and TMPRSS2 associated with COVID‐19 severity: A systematic review with meta‐analysis
W Saengsiwaritt, J Jittikoon… - Reviews in medical …, 2022 - Wiley Online Library
Abstract Novel coronavirus disease 2019 (COVID‐19) poses a global threat, due to its
fluctuating frequency and lethality. Published data revealed associations of COVID‐19 …
fluctuating frequency and lethality. Published data revealed associations of COVID‐19 …
COVID-19 and genetic variants of protein involved in the SARS-CoV-2 entry into the host cells
A Latini, E Agolini, A Novelli, P Borgiani, R Giannini… - Genes, 2020 - mdpi.com
The recent global COVID-19 public health emergency is caused by SARS-CoV-2 infections
and can manifest extremely variable clinical symptoms. Host human genetic variability could …
and can manifest extremely variable clinical symptoms. Host human genetic variability could …
TMPRSS2 polymorphism (rs12329760) and the severity of the COVID-19 in Iranian population
A Yaghoobi, JS Lord, JS Rezaiezadeh… - PLoS …, 2023 - journals.plos.org
Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) has been responsible for
the recent pandemic since early 2020. Due to the wide range of clinical symptoms of this …
the recent pandemic since early 2020. Due to the wide range of clinical symptoms of this …
Transmembrane serine protease 2 Polymorphisms and Susceptibility to Severe Acute Respiratory Syndrome Coronavirus Type 2 Infection: A German Case-Control …
K Schönfelder, K Breuckmann, C Elsner… - Frontiers in …, 2021 - frontiersin.org
The transmembrane serine protease 2 (TMPRSS2) is the major host protease that enables
entry of the severe acute respiratory syndrome coronavirus type 2 (SARS-CoV-2) into host …
entry of the severe acute respiratory syndrome coronavirus type 2 (SARS-CoV-2) into host …
[HTML][HTML] A common TMPRSS2 variant has a protective effect against severe COVID-19
A David, N Parkinson, TP Peacock… - Current research in …, 2022 - Elsevier
Background: The human protein transmembrane protease serine type 2 (TMPRSS2) plays a
key role in SARS-CoV-2 infection, as it is required to activate the virus' spike protein …
key role in SARS-CoV-2 infection, as it is required to activate the virus' spike protein …
Evolutionary history of type II transmembrane serine proteases involved in viral priming
Type II transmembrane serine proteases (TTSPs) are a family of trypsin-like membrane-
anchored serine proteases that play key roles in the regulation of some crucial processes in …
anchored serine proteases that play key roles in the regulation of some crucial processes in …
[HTML][HTML] Polymorphism of tmprss2 (rs12329760) but not ace2 (rs4240157), tmprss11a (rs353163) and cd147 (rs8259) is associated with the severity of COVID-19 in …
O Izmailova, O Shlykova, A Kabaliei… - Acta Bio Medica …, 2023 - ncbi.nlm.nih.gov
Methods: The study population consisted of the Ukrainian population with COVID-19:
patients without oxygen therapy (n= 62), with non-invasive (n= 92) and invasive (n= 35) …
patients without oxygen therapy (n= 62), with non-invasive (n= 92) and invasive (n= 35) …
Association of the transmembrane serine protease-2 (TMPRSS2) polymorphisms with COVID-19
R Posadas-Sánchez, JM Fragoso, F Sánchez-Muñoz… - Viruses, 2022 - mdpi.com
SARS-CoV-2 uses the ACE2 receptor and the cellular protease TMPRSS2 for entry into
target cells. The present study aimed to establish if the TMPRSS2 polymorphisms are …
target cells. The present study aimed to establish if the TMPRSS2 polymorphisms are …
Fully exploiting SNP arrays: a systematic review on the tools to extract underlying genomic structure
L Balagué-Dobón, A Cáceres… - Briefings in …, 2022 - academic.oup.com
Single nucleotide polymorphisms (SNPs) are the most abundant type of genomic variation
and the most accessible to genotype in large cohorts. However, they individually explain a …
and the most accessible to genotype in large cohorts. However, they individually explain a …