Epidemiology and prevention of prostate cancer

G Gandaglia, R Leni, F Bray, N Fleshner… - European urology …, 2021 - Elsevier
Abstract Context Worldwide, prostate cancer (PCa) represents the second most common
solid tumor in men. Objective To assess the geographical distribution of PCa …

[HTML][HTML] Epidemiology of prostate cancer

P Rawla - World journal of oncology, 2019 - ncbi.nlm.nih.gov
Prostate cancer is the second most frequent cancer diagnosis made in men and the fifth
leading cause of death worldwide. Prostate cancer may be asymptomatic at the early stage …

Obesity and prostate cancer: weighing the evidence

EH Allott, EM Masko, SJ Freedland - European urology, 2013 - Elsevier
CONTEXT: Obesity and prostate cancer (PCa) affect substantial proportions of Western
society. Mounting evidence, both epidemiologic and mechanistic, for an association …

Body mass index, prostate cancer–specific mortality, and biochemical recurrence: a systematic review and meta-analysis

Y Cao, J Ma - Cancer prevention research, 2011 - AACR
Increasing evidence suggested obesity, measured by body mass index (BMI), was
associated with prostate cancer–specific mortality, and its impact on biochemical recurrence …

Obesity and cancer: mechanistic insights from transdisciplinary studies

EH Allott, SD Hursting - Endocrine-related cancer, 2015 - erc.bioscientifica.com
Obesity is associated with a range of health outcomes that are of clinical and public health
significance, including cancer. Herein, we summarize epidemiologic and preclinical …

Prediagnostic body-mass index, plasma C-peptide concentration, and prostate cancer-specific mortality in men with prostate cancer: a long-term survival analysis

J Ma, H Li, E Giovannucci, L Mucci, W Qiu… - The lancet …, 2008 - thelancet.com
Background Excess body-mass index (BMI) has been associated with adverse outcomes in
prostate cancer, and hyperinsulinaemia is a candidate mediator, but prospective data are …

Underlying features of prostate cancer—statistics, risk factors, and emerging methods for its diagnosis

CV Berenguer, F Pereira, JS Câmara, JAM Pereira - Current Oncology, 2023 - mdpi.com
Prostate cancer (PCa) is the most frequently occurring type of malignant tumor and a leading
cause of oncological death in men. PCa is very heterogeneous in terms of grade …

Hypogonadotropic hypogonadism in men with diabesity

S Dhindsa, H Ghanim, M Batra, P Dandona - Diabetes care, 2018 - Am Diabetes Assoc
One-third of men with obesity or type 2 diabetes have subnormal free testosterone
concentrations. The lower free testosterone concentrations are observed in obese men at all …

Obesity increases the risk for high-grade prostate cancer: results from the REDUCE study

AC Vidal, LE Howard, DM Moreira… - … Biomarkers & Prevention, 2014 - AACR
Background: Studies suggest that obesity is associated with lower risk of prostate cancer but
more aggressive cancers. As obesity lowers PSA levels, these observations may be …

Mechanisms underlying the metabolic actions of testosterone in humans: a narrative review

P Dandona, S Dhindsa, H Ghanim… - Diabetes, Obesity and …, 2021 - Wiley Online Library
The role of testosterone in improving sexual symptoms in men with hypogonadism is well
known. However, recent studies indicate that testosterone plays an important role in several …