Chimeric antigen receptor T-cell therapies for lymphoma

JN Brudno, JN Kochenderfer - Nature reviews Clinical oncology, 2018 - nature.com
New therapies are needed for patients with Hodgkin or non-Hodgkin lymphomas that are
resistant to standard therapies. Indeed, unresponsiveness to standard chemotherapy and …

Modern radiation therapy for nodal non-Hodgkin lymphoma—target definition and dose guidelines from the International Lymphoma Radiation Oncology Group

T Illidge, L Specht, J Yahalom, B Aleman… - International Journal of …, 2014 - Elsevier
Radiation therapy (RT) is the most effective single modality for local control of non-Hodgkin
lymphoma (NHL) and is an important component of therapy for many patients. Many of the …

NCCN guidelines insights: B-cell lymphomas, version 3.2019: featured updates to the NCCN guidelines

AD Zelenetz, LI Gordon, JS Abramson… - Journal of the National …, 2019 - jnccn.org
Diffuse large B-cell lymphomas (DLBCLs) and follicular lymphoma (FL) are the most
common subtypes of B-cell non-Hodgkin's lymphomas in adults. Histologic transformation of …

Rituximab and ICE as second-line therapy before autologous stem cell transplantation for relapsed or primary refractory diffuse large B-cell lymphoma

T Kewalramani, AD Zelenetz, SD Nimer, C Portlock… - Blood, 2004 - ashpublications.org
Patients with relapsed or primary refractory diffuse large B-cell lymphoma (DLBCL) who
achieve complete response (CR) before autologous stem cell transplantation (ASCT) …

[PDF][PDF] Guidelines for the management of diffuse large B-cell lymphoma

S Chaganti, T Illidge, S Barrington, P Mckay… - Br J …, 2016 - discovery.ucl.ac.uk
1Department of Haematology, Queen Elizabeth Hospital, Birmingham, 2Department of
Clinical Oncology, Christie Hospital, Manchester, 3PET Imaging Centre, King's College …

Improving outcomes for patients with diffuse large B‐cell lymphoma

CR Flowers, R Sinha, JM Vose - CA: a cancer journal for …, 2010 - Wiley Online Library
Diffuse large B‐cell lymphoma (DLBCL) is the most commonly occurring form of non‐
Hodgkin lymphoma in the western world. Until the mid 1990s the incidence of DLBCL …

Age-adjusted International Prognostic Index predicts autologous stem cell transplantation outcome for patients with relapsed or primary refractory diffuse large B-cell …

PA Hamlin, AD Zelenetz, T Kewalramani, J Qin… - Blood, 2003 - ashpublications.org
Second-line chemotherapy followed by high-dose therapy (HDT) with autologous stem cell
transplantation (ASCT) cures less than half of the patients with relapsed or refractory diffuse …

Phase III randomized study of rituximab/carmustine, etoposide, cytarabine, and melphalan (BEAM) compared with iodine-131 tositumomab/BEAM with autologous …

JM Vose, S Carter, LJ Burns, E Ayala… - Journal of Clinical …, 2013 - ascopubs.org
Purpose This clinical trial evaluated standard-dose radioimmunotherapy with a
chemotherapy-based transplantation regimen followed by autologous hematopoietic cell …

[HTML][HTML] Early failure of frontline rituximab-containing chemo-immunotherapy in diffuse large B cell lymphoma does not predict futility of autologous hematopoietic cell …

M Hamadani, PN Hari, Y Zhang, J Carreras… - Biology of Blood and …, 2014 - Elsevier
The poor prognosis for patients with diffuse large B cell lymphoma (DLBCL) who relapse
within 1 year of initial diagnosis after first-line rituximab-based chemo-immunotherapy has …

Long-term survival and cost-effectiveness associated with axicabtagene ciloleucel vs chemotherapy for treatment of B-cell lymphoma

MD Whittington, RB McQueen, DA Ollendorf… - JAMA network …, 2019 - jamanetwork.com
Importance Axicabtagene ciloleucel, a chimeric antigen receptor T-cell therapy, represents a
new and potentially curative treatment option for B-cell lymphoma. It is expected to have …