Current developments of coumarin compounds in medicinal chemistry

XM Peng, G LV Damu, H Zhou - Current pharmaceutical …, 2013 - ingentaconnect.com
Coumarin compounds represent an important type of naturally occurring and synthetic
oxygen-containing heterocycles with typical benzopyrone framework. This type of special …

Pharmacological and nutritional effects of natural coumarins and their structure–activity relationships

JJ Zhu, JG Jiang - Molecular nutrition & food research, 2018 - Wiley Online Library
Coumarins are fused benzene and pyrone ring systems with a wide spectrum of
bioactivities, including antitumor, anti‐inflammation, antiviral, and antibacterial effects. In this …

Influence of azo-based donor modifications on nonlinear optical amplitude of D-π-A based organic chromophores: A DFT/TD-DFT exploration

I Shafiq, I Amanat, M Khalid, MA Asghar, R Baby… - Synthetic Metals, 2023 - Elsevier
Organic heterocyclic fused ring compounds possess remarkable nonlinear optical (NLO)
amplitude, are potentially employed in optical computing and nano-photonics. Herein …

Interaction of coumarin with calf thymus DNA: deciphering the mode of binding by in vitro studies

T Sarwar, SU Rehman, MA Husain, HM Ishqi… - International journal of …, 2015 - Elsevier
DNA is the major target for a wide range of therapeutic substances. Thus, there has been
considerable interest in the binding studies of small molecules with DNA. Interaction …

Coumarin: a promising scaffold for anticancer agents

M Kaur, S Kohli, S Sandhu, Y Bansal… - Anti-Cancer Agents in …, 2015 - ingentaconnect.com
Coumarin enjoys an important place in drug discovery process due to its presence in
diversity of biologically active compounds. Many compounds of plant origin are derivatives …

Conformational fidelity and hydrogen bond associability of L-histidine with sulfamate anion studied through XRD, quantum chemical, spectroscopic and molecular …

A Zochedh, A Shunmuganarayanan… - Journal of Molecular …, 2023 - Elsevier
Abstract L-histidinium sulfamate,(C 6 H 10 N 3 O 2)+. SO 3 NH 2−, crystallizes in the
orthorhombic space group, P2 1 2 1 2 1, with four molecules per unit cell. The asymmetric …

[PDF][PDF] Antioxidant activity of coumarins

Y Al-Majedy, A Al-Amiery, AA Kadhum… - Systematic Reviews in …, 2017 - academia.edu
Coumarins are heterocyclic molecules that have been associated with beneficial effects on
human health, such as reducing the risk of cancer, diabetes, cardiovascular and brain …

Spectroscopic characterization, cyclic voltammetry, biological investigations, MOE, and gaussian calculations of VO (II), Cu (II), and Cd (II) heteroleptic complexes

AG Al-Harazie, EA Gomaa, RR Zaky… - ACS …, 2023 - ACS Publications
A novel hydrazone ligand (o-H2BMP) N-(benzo [d] thiazol-2-yl)-3-oxo-3-(2-(1-(pyridin-2-yl)
ethylidene) hydrazinyl) propanamide alongside its Cu (II), Cd (II), and VO (II) complexes …

Computational studies on the doped graphene quantum dots as potential carriers in drug delivery systems for isoniazid drug

M Vatanparast, Z Shariatinia - Structural Chemistry, 2018 - Springer
In this study, the application of graphene quantum dots (GQDs) and doped GQDs as
potential carriers for the delivery of isoniazid (Iso) drug has been investigated, using density …

Heterocyclic antioxidants in nature: coumarins

MJ Matos, S Vazquez-Rodriguez… - Current Organic …, 2017 - ingentaconnect.com
Coumarins represent an important family of naturally occurring and/or synthetic oxygen-
containing heterocycles, bearing a characteristic benzopyrone framework. These …