Recent advances in hyperthermia therapy‐based synergistic immunotherapy

M Chang, Z Hou, M Wang, C Li, J Lin - Advanced Materials, 2021 - Wiley Online Library
The past decades have witnessed hyperthermia therapy (HTT) as an emerging strategy
against malignant tumors. Nanomaterial‐based photothermal therapy (PTT) and magnetic …

Cancer vaccine therapeutics: limitations and effectiveness—A literature review

M Kaczmarek, J Poznańska, F Fechner, N Michalska… - Cells, 2023 - mdpi.com
In recent years, there has been a surge of interest in tumor microenvironment-associated
cancer vaccine therapies. These innovative treatments aim to activate and enhance the …

[HTML][HTML] Machine learning identifies stemness features associated with oncogenic dedifferentiation

TM Malta, A Sokolov, AJ Gentles, T Burzykowski… - Cell, 2018 - cell.com
Cancer progression involves the gradual loss of a differentiated phenotype and acquisition
of progenitor and stem-cell-like features. Here, we provide novel stemness indices for …

Restoring tumor immunogenicity with dendritic cell reprogramming

O Zimmermannova, AG Ferreira, E Ascic… - Science …, 2023 - science.org
Decreased antigen presentation contributes to the ability of cancer cells to evade the
immune system. We used the minimal gene regulatory network of type 1 conventional …

B cells and T follicular helper cells mediate response to checkpoint inhibitors in high mutation burden mouse models of breast cancer

DP Hollern, N Xu, A Thennavan, C Glodowski… - Cell, 2019 - cell.com
This study identifies mechanisms mediating responses to immune checkpoint inhibitors
using mouse models of triple-negative breast cancer. By creating new mammary tumor …

High-dose vitamin C enhances cancer immunotherapy

A Magrì, G Germano, A Lorenzato, S Lamba… - Science translational …, 2020 - science.org
Vitamin C (VitC) is known to directly impair cancer cell growth in preclinical models, but
there is little clinical evidence on its antitumoral efficacy. In addition, whether and how VitC …

Human iPSC banking: barriers and opportunities

CY Huang, CL Liu, CY Ting, YT Chiu… - Journal of biomedical …, 2019 - Springer
The introduction of induced pluripotent stem cells (iPSCs) has opened up the potential for
personalized cell therapies and ushered in new opportunities for regenerative medicine …

Engineered TCR-T cell immunotherapy in anticancer precision medicine: pros and cons

Q Zhao, Y Jiang, S Xiang, PJ Kaboli, J Shen… - Frontiers in …, 2021 - frontiersin.org
This review provides insight into the role of engineered T-cell receptors (TCRs) in
immunotherapy. Novel approaches have been developed to boost anticancer immune …

Recent progress of stem cell therapy in cancer treatment: molecular mechanisms and potential applications

DT Chu, TT Nguyen, NLB Tien, DK Tran, JH Jeong… - Cells, 2020 - mdpi.com
The insufficient and unspecific target of traditional therapeutic approaches in cancer
treatment often leads to therapy resistance and cancer recurrence. Over the past decades …

Exploring the promising potential of induced pluripotent stem cells in cancer research and therapy

M Chehelgerdi, F Behdarvand Dehkordi… - Molecular Cancer, 2023 - Springer
The advent of iPSCs has brought about a significant transformation in stem cell research,
opening up promising avenues for advancing cancer treatment. The formation of cancer is a …