The recent convergence between physics and biology has led many physicists to enter the
fields of cell and developmental biology. One of the most exciting areas of interest has been …

Organ-on-chip devices have provided the pharmaceutical and tissue engineering worlds
much hope since they arrived and began to grow in sophistication. However, limitations for …

The stiffness sensing ability is required to respond to the stiffness of the matrix. Here we
determined whether normal cells and cancer cells display distinct mechanical phenotypes …

The rapidly growing field of mechanobiology demands for robust and reproducible
characterization of cell mechanical properties. Recent achievements in understanding the …

Tumors are not merely cancerous cells that undergo mindless proliferation. Rather, they are
highly organized and interconnected organ systems. Tumor cells reside in complex …

Throughout history, capillary systems have aided the establishment of the fundamental laws
of blood flow and its non-Newtonian properties. The advent of microfluidics technology in the …

The rapid development of micro/nanoengineered functional biomaterials in the last two
decades has empowered materials scientists and bioengineers to precisely control different …

While performing several functions, adherent cells deform their surrounding substrate via
stable adhesions that connect the intracellular cytoskeleton to the extracellular matrix. The …

We describe a novel mechanical characterization method that has directly measured the
stiffness of cancer spheroids for the first time to our knowledge. Stiffness is known to be a …

Since the early 2000s, microfluidic cell culture systems have attracted significant attention as
a promising alternative to conventional cell culture methods and the importance of designing …