Tolerance and resistance of microbial biofilms

O Ciofu, C Moser, PØ Jensen, N Høiby - Nature Reviews Microbiology, 2022 - nature.com
Chronic infections caused by microbial biofilms represent an important clinical challenge.
The recalcitrance of microbial biofilms to antimicrobials and to the immune system is a major …

Mechanisms of antimicrobial resistance in biofilms

HY Liu, EL Prentice, MA Webber - npj Antimicrobials and Resistance, 2024 - nature.com
Most bacteria in nature exist in aggregated communities known as biofilms, and cells within
a biofilm demonstrate major physiological changes compared to their planktonic …

Role played by the environment in the emergence and spread of antimicrobial resistance (AMR) through the food chain

EFSA Panel on Biological Hazards (BIOHAZ)… - Efsa …, 2021 - Wiley Online Library
The role of food‐producing environments in the emergence and spread of antimicrobial
resistance (AMR) in EU plant‐based food production, terrestrial animals (poultry, cattle and …

Intermittent antibiotic treatment of bacterial biofilms favors the rapid evolution of resistance

M Usui, Y Yoshii, S Thiriet-Rupert, JM Ghigo… - Communications …, 2023 - nature.com
Bacterial antibiotic resistance is a global health concern of increasing importance and
intensive study. Although biofilms are a common source of infections in clinical settings, little …

Biofilm antimicrobial susceptibility through an experimental evolutionary lens

T Coenye, M Bové, T Bjarnsholt - NPJ biofilms and microbiomes, 2022 - nature.com
Experimental evolution experiments in which bacterial populations are repeatedly exposed
to an antimicrobial treatment, and examination of the genotype and phenotype of the …

Trans-kingdom interactions in mixed biofilm communities

FA Sadiq, MF Hansen, M Burmølle… - FEMS microbiology …, 2022 - academic.oup.com
The microbial world represents a phenomenal diversity of microorganisms from different
kingdoms of life, which occupy an impressive set of ecological niches. Most, if not all …

[HTML][HTML] Salmonella spp. quorum sensing: an overview from environmental persistence to host cell invasion

A Sholpan, A Lamas, A Cepeda, CM Franco - AIMS microbiology, 2021 - ncbi.nlm.nih.gov
Salmonella spp. is one of the main foodborne pathogens around the world. It has a cyclic
lifestyle that combines host colonization with survival outside the host, implying that …

Antibiotic cycling affects resistance evolution independently of collateral sensitivity

P Brepoels, K Appermans… - Molecular Biology …, 2022 - academic.oup.com
Antibiotic cycling has been proposed as a promising approach to slow down resistance
evolution against currently employed antibiotics. It remains unclear, however, to which …

Biofilm characteristics and transcriptomic profiling of Acinetobacter johnsonii defines signatures for planktonic and biofilm cells

J Jia, X Xue, Y Guan, X Fan, Z Wang - Environmental Research, 2022 - Elsevier
Most bacteria in the natural environment have a biofilm mode of life, which is intrinsically
tolerant to antibiotics. While until now, the knowledge of biofilm formation by Acinetobacter …

[HTML][HTML] Biofilm tolerance, resistance and infections increasing threat of public health

S Yang, X Li, W Cang, D Mu, S Ji, Y An, R Wu… - Microbial Cell, 2023 - ncbi.nlm.nih.gov
Microbial biofilms can cause chronic infection. In the clinical setting, the biofilm-related
infections usually persist and reoccur; the main reason is the increased antibiotic resistance …