Young-onset colorectal cancer

MCW Spaander, AG Zauber, S Syngal… - Nature reviews Disease …, 2023 - nature.com
In the past decades the incidence of colorectal cancer (CRC) in people under the age of 50
years has increased, which is referred to as early-onset CRC or young-onset CRC (YO …

Impact of bacterial metabolites on gut barrier function and host immunity: a focus on bacterial metabolism and its relevance for intestinal inflammation

N Gasaly, P De Vos, MA Hermoso - Frontiers in immunology, 2021 - frontiersin.org
The diverse and dynamic microbial community of the human gastrointestinal tract plays a
vital role in health, with gut microbiota supporting the development and function of the gut …

[HTML][HTML] Role of microbiota-derived short-chain fatty acids in cancer development and prevention

R Mirzaei, A Afaghi, S Babakhani, MR Sohrabi… - Biomedicine & …, 2021 - Elsevier
Following cancer, cells in a particular tissue can no longer respond to the factors involved in
controlling cell survival, differentiation, proliferation, and death. In recent years, it has been …

Global burden of colorectal cancer: emerging trends, risk factors and prevention strategies

NN Keum, E Giovannucci - Nature reviews Gastroenterology & …, 2019 - nature.com
Globally, colorectal cancer (CRC) is the third most commonly diagnosed malignancy and the
second leading cause of cancer death. Arising through three major pathways, including …

Butyrate-producing human gut symbiont, Clostridium butyricum, and its role in health and disease

MK Stoeva, J Garcia-So, N Justice, J Myers, S Tyagi… - Gut …, 2021 - Taylor & Francis
Clostridium butyricum is a butyrate-producing human gut symbiont that has been safely
used as a probiotic for decades. C. butyricum strains have been investigated for potential …

Carbohydrate quality and human health: a series of systematic reviews and meta-analyses

A Reynolds, J Mann, J Cummings, N Winter, E Mete… - The Lancet, 2019 - thelancet.com
Background Previous systematic reviews and meta-analyses explaining the relationship
between carbohydrate quality and health have usually examined a single marker and a …

Colorectal cancer and nutrition

K Thanikachalam, G Khan - Nutrients, 2019 - mdpi.com
Colorectal Cancer is the third most common cancer diagnosed in the US. While the
incidence and the mortality rate of colorectal cancer has decreased due to effective cancer …

The effects of different dietary fiber pectin structures on the gastrointestinal immune barrier: impact via gut microbiota and direct effects on immune cells

M Beukema, MM Faas, P de Vos - Experimental & Molecular Medicine, 2020 - nature.com
Pectins are dietary fibers with different structural characteristics. Specific pectin structures
can influence the gastrointestinal immune barrier by directly interacting with immune cells or …

Dietary fiber in the prevention of obesity and obesity-related chronic diseases: From epidemiological evidence to potential molecular mechanisms

IS Waddell, C Orfila - Critical reviews in food science and nutrition, 2023 - Taylor & Francis
Obesity is a mostly preventable diet-related disease and currently a major challenge for
human populations worldwide. Obesity is a major risk factor for diseases such as type 2 …

The Western diet–microbiome-host interaction and its role in metabolic disease

MK Zinöcker, IA Lindseth - Nutrients, 2018 - mdpi.com
The dietary pattern that characterizes the Western diet is strongly associated with obesity
and related metabolic diseases, but biological mechanisms supporting these associations …