Optimization of metabolomic data processing using NOREVA

J Fu, Y Zhang, Y Wang, H Zhang, J Liu, J Tang… - Nature protocols, 2022 - nature.com
A typical output of a metabolomic experiment is a peak table corresponding to the intensity
of measured signals. Peak table processing, an essential procedure in metabolomics, is …

A review on quantitative multiplexed proteomics

N Pappireddi, L Martin, M Wühr - Chembiochem, 2019 - Wiley Online Library
Over the last few decades, mass spectrometry‐based proteomics has become an
increasingly powerful tool that is now able to routinely detect and quantify thousands of …

[HTML][HTML] Pan-cancer proteomic map of 949 human cell lines

E Gonçalves, RC Poulos, Z Cai, S Barthorpe… - Cancer Cell, 2022 - cell.com
The proteome provides unique insights into disease biology beyond the genome and
transcriptome. A lack of large proteomic datasets has restricted the identification of new …

A metabolomics comparison of plant-based meat and grass-fed meat indicates large nutritional differences despite comparable Nutrition Facts panels

S van Vliet, JR Bain, MJ Muehlbauer, FD Provenza… - Scientific reports, 2021 - nature.com
A new generation of plant-based meat alternatives—formulated to mimic the taste and
nutritional composition of red meat—have attracted considerable consumer interest …

Machine learning applications for mass spectrometry-based metabolomics

UW Liebal, ANT Phan, M Sudhakar, K Raman… - Metabolites, 2020 - mdpi.com
The metabolome of an organism depends on environmental factors and intracellular
regulation and provides information about the physiological conditions. Metabolomics helps …

Bioinformatics methods for mass spectrometry-based proteomics data analysis

C Chen, J Hou, JJ Tanner, J Cheng - International journal of molecular …, 2020 - mdpi.com
Recent advances in mass spectrometry (MS)-based proteomics have enabled tremendous
progress in the understanding of cellular mechanisms, disease progression, and the …

MetOrigin: discriminating the origins of microbial metabolites for integrative analysis of the gut microbiome and metabolome

G Yu, C Xu, D Zhang, F Ju, Y Ni - IMeta, 2022 - Wiley Online Library
The interactions between the gut microbiome and metabolome play an important role in
human health and diseases. Current studies mainly apply statistical correlation analysis …

Plasma metabolomic profiles associated with mortality and longevity in a prospective analysis of 13,512 individuals

F Wang, AJ Tessier, L Liang, C Wittenbecher… - Nature …, 2023 - nature.com
Experimental studies reported biochemical actions underpinning aging processes and
mortality, but the relevant metabolic alterations in humans are not well understood. Here we …

Nutrimetabolomics: an integrative action for metabolomic analyses in human nutritional studies

MM Ulaszewska, CH Weinert… - Molecular nutrition & …, 2019 - Wiley Online Library
The life sciences are currently being transformed by an unprecedented wave of
developments in molecular analysis, which include important advances in instrumental …

Prenatal exposure to perfluoroalkyl substances associated with increased susceptibility to liver injury in children

N Stratakis, DV Conti, R Jin, K Margetaki, D Valvi… - Hepatology, 2020 - journals.lww.com
The severe acute respiratory syndrome coronavirus 2 pandemic has drastically altered all
facets of clinical care and research. Clinical research in hepatology has had a rich tradition …