Arginine and endothelial function
J Gambardella, W Khondkar, MB Morelli, X Wang… - Biomedicines, 2020 - mdpi.com
Arginine (L-arginine), is an amino acid involved in a number of biological processes,
including the biosynthesis of proteins, host immune response, urea cycle, and nitric oxide …
including the biosynthesis of proteins, host immune response, urea cycle, and nitric oxide …
Oxidative stress and vascular inflammation in aging
M El Assar, J Angulo, L Rodríguez-Mañas - Free Radical Biology and …, 2013 - Elsevier
Vascular aging, a determinant factor for cardiovascular disease and health status in the
elderly, is now viewed as a modifiable risk factor. Impaired endothelial vasodilation is a early …
elderly, is now viewed as a modifiable risk factor. Impaired endothelial vasodilation is a early …
l-Citrulline Supplementation: Impact on Cardiometabolic Health
Diminished bioavailability of nitric oxide (NO), the gaseous signaling molecule involved in
the regulation of numerous vital biological functions, contributes to the development and …
the regulation of numerous vital biological functions, contributes to the development and …
Mechanisms and clinical implications of endothelial dysfunction in arterial hypertension
P Ambrosino, T Bachetti, SE D'Anna… - Journal of …, 2022 - mdpi.com
The endothelium is composed of a monolayer of endothelial cells, lining the interior surface
of blood and lymphatic vessels. Endothelial cells display important homeostatic functions …
of blood and lymphatic vessels. Endothelial cells display important homeostatic functions …
Aging and vascular endothelial function in humans
Advancing age is the major risk factor for the development of CVD (cardiovascular
diseases). This is attributable, in part, to the development of vascular endothelial …
diseases). This is attributable, in part, to the development of vascular endothelial …
Direct evidence of endothelial oxidative stress with aging in humans: relation to impaired endothelium-dependent dilation and upregulation of nuclear factor-κB
Aging is associated with impaired vascular endothelial function, as indicated in part by
reduced endothelium-dependent dilation (EDD). Decreased EDD with aging is thought to be …
reduced endothelium-dependent dilation (EDD). Decreased EDD with aging is thought to be …
Inflammation and endothelial dysfunction during aging: role of NF-κB
A Csiszar, M Wang, EG Lakatta… - Journal of applied …, 2008 - journals.physiology.org
One of the major conceptual advances in our understanding of the pathogenesis of age-
associated cardiovascular diseases has been the insight that age-related oxidative stress …
associated cardiovascular diseases has been the insight that age-related oxidative stress …
Endothelial dysfunction and aging: an update
MD Herrera, C Mingorance… - Ageing research …, 2010 - Elsevier
Aging is an important risk factor for the development of many cardiovascular diseases as
atherosclerosis and hypertension with a common underlying circumstance: the progressive …
atherosclerosis and hypertension with a common underlying circumstance: the progressive …
NADPH oxidase-dependent signaling in endothelial cells: role in physiology and pathophysiology
RS Frey, M Ushio–Fukai, AB Malik - Antioxidants & redox signaling, 2009 - liebertpub.com
Reactive oxygen species (ROS) including superoxide (O2.−) and hydrogen peroxide (H2O2)
are produced endogenously in response to cytokines, growth factors; G-protein coupled …
are produced endogenously in response to cytokines, growth factors; G-protein coupled …
Acute effect of a high nitrate diet on brain perfusion in older adults
TD Presley, AR Morgan, E Bechtold, W Clodfelter… - Nitric Oxide, 2011 - Elsevier
AIMS: Poor blood flow and hypoxia/ischemia contribute to many disease states and may
also be a factor in the decline of physical and cognitive function in aging. Nitrite has been …
also be a factor in the decline of physical and cognitive function in aging. Nitrite has been …