Mitochondria are structurally and functionally distinct organelles that produce adenosine
triphosphate (ATP) through oxidative phosphorylation (OXPHOS), to provide energy to …

Abstract Phosphodiesterase 5 (PDE5) is one of the most well-studied phosphodiesterases
(PDEs) that specifically targets cGMP typically generated by nitric oxide (NO)-mediated …

Reactive oxygen species (ROS) play an important role in male fertility. Overproduction of
reactive oxygen species (ROS) has been associated with a variety of male fertility …

A unique characteristic of mammalian sperm thermotaxis is extreme temperature sensitivity,
manifested by the capacity of spermatozoa to respond to temperature changes of< 0.0006° …

Nitric oxide (NO), a modulator of several physiological processes, is involved in different
human sperm functions. We have investigated whether NO may stimulate the motility of …

Introduction: Male factor infertility contributes partially and solely to the problem of
childlessness in around 50% of the cases. Unfortunately, 30–50% of the etiologies of male …

Reproductive proteins are amongst the most evolutionarily divergent proteins known, and
research on genetically well‐characterized species suggests that postcopulatory sexual …

Recently, various opsin types, known to be involved in vision, were demonstrated to be
present in human and mouse sperm cells and to be involved there in thermosensing for …

Summary The phosphodiesterase type 5 (PDE5) inhibitor, Sildenafil, is a novel, oral
treatment approach for pulmonary hypertension. As Leydig cells present PDE5, this study …

Abstract Introduction Sexual dysfunctions (SDs) have been frequently reported among male
partners of infertile couples due to psychogenic, relational and/or organic issues related with …