[HTML][HTML] Oxidative stress in the eye and its role in the pathophysiology of ocular diseases

EW Böhm, F Buonfiglio, AM Voigt, P Bachmann, T Safi… - Redox Biology, 2023 - Elsevier
Oxidative stress occurs through an imbalance between the generation of reactive oxygen
species (ROS) and the antioxidant defense mechanisms of cells. The eye is particularly …

Aging, oxidative stress and degenerative diseases: mechanisms, complications and emerging therapeutic strategies

MR Chaudhary, S Chaudhary, Y Sharma, TA Singh… - Biogerontology, 2023 - Springer
Aging accompanied by several age-related complications, is a multifaceted inevitable
biological progression involving various genetic, environmental, and lifestyle factors. The …

Quercetin remodels the tumor microenvironment to improve the permeation, retention, and antitumor effects of nanoparticles

K Hu, L Miao, TJ Goodwin, J Li, Q Liu, L Huang - ACS nano, 2017 - ACS Publications
Our previous work demonstrated that Wnt16 expression in cisplatin-damaged tumor-
associated fibroblasts is a key factor contributing to cisplatin resistance in malignancies …

Role of oxidative stress in ocular diseases: a balancing act

DY Shu, S Chaudhary, KS Cho, A Lennikov, WP Miller… - Metabolites, 2023 - mdpi.com
Redox homeostasis is a delicate balancing act of maintaining appropriate levels of
antioxidant defense mechanisms and reactive oxidizing oxygen and nitrogen species. Any …

[HTML][HTML] The therapeutic use of quercetin in ophthalmology: Recent applications

L Zhao, H Wang, X Du - Biomedicine & Pharmacotherapy, 2021 - Elsevier
Quercetin is a natural flavonol antioxidant found in various plant sources and food samples.
It is well known for its notable curative effects on the treatment of ophthalmic diseases due to …

Nutritional and metabolic imbalance in keratoconus

RM Lasagni Vitar, F Bonelli, P Rama, G Ferrari - Nutrients, 2022 - mdpi.com
Keratoconus (KC) is a progressive corneal degeneration characterized by structural
changes consisting of progressive thinning and steepening of the cornea. These alterations …

Quercetin and its natural sources in wound healing management

N Polerà, M Badolato, F Perri… - Current Medicinal …, 2019 - ingentaconnect.com
Giving a glance to the report of Wound Care Market by Product updated in 2017, we can see
that wound care market is expected to reach USD 22.01 billion by 2022 from USD 18.35 …

Mechanisms of collagen crosslinking in diabetes and keratoconus

TB McKay, S Priyadarsini, D Karamichos - Cells, 2019 - mdpi.com
Collagen crosslinking provides the mechanical strength required for physiological
maintenance of the extracellular matrix in most tissues in the human body, including the …

Dengue Fever: Therapeutic Potential of Carica papaya L. Leaves

MMR Sarker, F Khan, IN Mohamed - Frontiers in pharmacology, 2021 - frontiersin.org
Dengue, a very widespread mosquito-borne infectious disease caused by Aedes aegypti
virus, has been occurring during the monsoons every year. The prevalence and incidence of …

Quercetin and related analogs as therapeutics to promote tissue repair

TB McKay, KA Emmitte, C German, D Karamichos - Bioengineering, 2023 - mdpi.com
Quercetin is a polyphenol of the flavonoid class of secondary metabolites that is widely
distributed in the plant kingdom. Quercetin has been found to exhibit potent bioactivity in the …