Imaging techniques in Alzheimer's disease: a review of applications in early diagnosis and longitudinal monitoring

WM van Oostveen, ECM de Lange - International journal of molecular …, 2021 - mdpi.com
Background. Alzheimer's disease (AD) is a progressive neurodegenerative disorder
affecting many individuals worldwide with no effective treatment to date. AD is characterized …

Understanding the relationships between physiological and psychosocial stress, cortisol and cognition

KA James, JI Stromin, N Steenkamp… - Frontiers in …, 2023 - frontiersin.org
Stress is viewed as a state of real or perceived threat to homeostasis, the management of
which involves the endocrine, nervous, and immune systems. These systems work …

Brain imaging in Alzheimer disease

KA Johnson, NC Fox… - Cold Spring …, 2012 - perspectivesinmedicine.cshlp.org
Imaging has played a variety of roles in the study of Alzheimer disease (AD) over the past
four decades. Initially, computed tomography (CT) and then magnetic resonance imaging …

Cognitive reserve in aging

AM Tucker, Y Stern - Current Alzheimer Research, 2011 - ingentaconnect.com
Cognitive reserve explains why those with higher IQ, education, occupational attainment, or
participation in leisure activities evidence less severe clinical or cognitive changes in the …

Brain structure and obesity

CA Raji, AJ Ho, NN Parikshak, JT Becker… - Human brain …, 2010 - Wiley Online Library
Obesity is associated with increased risk for cardiovascular health problems including
diabetes, hypertension, and stroke. These cardiovascular afflictions increase risk for …

DTI measures in crossing-fibre areas: increased diffusion anisotropy reveals early white matter alteration in MCI and mild Alzheimer's disease

G Douaud, S Jbabdi, TEJ Behrens, RA Menke, A Gass… - Neuroimage, 2011 - Elsevier
Though mild cognitive impairment is an intermediate clinical state between healthy aging
and Alzheimer's disease (AD), there are very few whole-brain voxel-wise diffusion MRI …

The Alzheimer's Disease Neuroimaging Initiative: a review of papers published since its inception

MW Weiner, DP Veitch, PS Aisen, LA Beckett… - Alzheimer's & …, 2013 - Elsevier
Abstract The Alzheimer's Disease Neuroimaging Initiative (ADNI) is an ongoing,
longitudinal, multicenter study designed to develop clinical, imaging, genetic, and …

MRI of hippocampal volume loss in early Alzheimer's disease in relation to ApoE genotype and biomarkers

N Schuff, N Woerner, L Boreta, T Kornfield, LM Shaw… - Brain, 2009 - academic.oup.com
Hippocampal volume change over time, measured with MRI, has huge potential as a marker
for Alzheimer's disease. The objectives of this study were:(i) to test if constant and …

Baseline MRI predictors of conversion from MCI to probable AD in the ADNI cohort

SL Risacher, AJ Saykin, JD Wes, L Shen… - Current Alzheimer …, 2009 - ingentaconnect.com
The Alzheimer's Disease Neuroimaging Initiative (ADNI) is a multi-center study assessing
neuroimaging in diagnosis and longitudinal monitoring. Amnestic Mild Cognitive Impairment …

Predictive markers for AD in a multi-modality framework: an analysis of MCI progression in the ADNI population

C Hinrichs, V Singh, G Xu, SC Johnson… - Neuroimage, 2011 - Elsevier
Alzheimer's Disease (AD) and other neurodegenerative diseases affect over 20 million
people worldwide, and this number is projected to significantly increase in the coming …