Early life stress (ELS), such as abuse and neglect during childhood, can lead to psychiatric
disorders in later life. Previous studies have suggested that ELS can cause profound …

Recent studies have revealed that patients with psychiatric disorders have altered
microRNA (miRNA) expression profiles in the circulation and brain. Furthermore, animal …

The etiology of schizophrenia (SCZ) is regarded as one of the most fundamental puzzles in
current medical research, and its diagnosis is limited by the lack of objective molecular …

Growing evidences suggest that sustained neuroinflammation, caused by microglia
overactivation, is implicated in the development and aggravation of several neurological and …

Schizophrenia is a severe psychiatric disorder with a complex array of signs and symptoms
that causes very significant disability in young people. While schizophrenia has a strong …

Aim Symptoms of bipolar disorder (BD) include changes in mood, activity, energy, sleep,
and appetite. Since many of these processes are regulated by circadian function, circadian …

Genetic (G) and environmental (E) factors are involved in the etiology and course of the
major psychoses (MP), ie major depressive disorder (MDD), bipolar disorder (BD) …

Chronic stress-induced aberrant gene expression in the brain and subsequent dysfunctional
neuronal plasticity have been implicated in the etiology and pathophysiology of mood …

Some neuropsychiatric disease, including schizophrenia, may originate during prenatal
development, following periods of gestational hypoxia and placental oxidative stress. Here …

Depression is the leading psychiatric disorder worldwide with a significant economic and
emotional strain on society. There is a need for robust biomarkers which will help improve …