The discovery of leptin was intrinsically associated with its ability to regulate body weight.
However, the effects of leptin are more far-reaching and include profound glucose-lowering …

Leptin and its receptors have been identified as key regulators of body weight and energy
homeostasis. A decrease in tissue sensitivity to leptin leads to the development of obesity …

Under normal physiological conditions, leptin and the leptin receptor (ObR) regulate the
body weight by balancing food intake and energy expenditure. However, this adipocyte …

It is now established that adipose tissue, skeletal muscle, and heart are endocrine organs
and secrete in normal and in pathological conditions several molecules, called, respectively …

The blood–brain barrier (BBB) is a protective endothelial barrier lining the brain
microvasculature which prevents brain delivery of therapies against brain diseases. Hence …

A limitation for recombinant adeno-associated virus (rAAV)-mediated gene transfer into the
central nervous system (CNS) is the low penetration of vectors across the human blood …

The choroid plexus (CP) of the blood-cerebrospinal fluid barrier (BCSFB) impacts CSF
homeostasis, brain diseases, and neuromedical translation. CP executes neuroendocrine …

Drug‐carrying nanoparticles are a promising strategy to deliver therapeutics into the brain,
but their translation requires better characterization of interactions between nanomaterials …

Nanoparticles capable of penetrating the blood–brain barrier (BBB) will greatly advance the
delivery of therapies against brain disorders. Carbon nanotubes hold great potential as …

Ethnopharmacological relevance The medicinal properties of grapes (Vitis vinifera L.) are
well known since ancient times. Ethnobotanical grape preparations, like the Ayurvedic …