Gold nanoparticles (AuNPs) are of increasing interest for their unique properties and their
biocompatability, minimal toxicity, multivalency and size tunability make them exciting drug …

Targeting of radionuclides with antibodies, or radioimmunotherapy, has been an active field
of research spanning nearly 50 years, evolving with advancing technologies in molecular …

Background Prostate-specific membrane antigen (PSMA) is a promising target for
diagnostics and therapy of prostate carcinoma (PCa). Based on the hypothesis that PSMA …

The epidermal growth factor receptor (EGFR) has evolved over years into a main molecular
target for the treatment of different cancer entities. In this regard, the anti-EGFR antibody …

Mitochondria as one of the key subcellular organelles have been well recognized as a
promising druggable target and are closely associated with energy supply and various …

Purpose Radionuclide therapy (RNT) is a rapidly growing area of clinical nuclear medicine,
wherein radionuclides are employed to deliver cytotoxic dose of radiation to the diseased …

The efficacy of external beam radiotherapy (EBRT) is dose dependent, but the dose that can
be applied to solid tumour lesions is limited by the sensitivity of the surrounding tissue. The …

Targeting epidermal growth factor receptor (EGFR)‐overexpressing tumors with
radiolabeled anti‐EGFR antibodies is a promising strategy for combination with external …

Background and Purpose: The addition of systemic drugs to whole-brain irradiation has not
improved the survival of patients with multiple brain metastases, most likely because the …

Background Cetuximab has demonstrated improved efficacy in combination with
chemotherapy and radiotherapy. We evaluated the integration of cetuximab in the combined …