Variability characterizes the complexity of biological systems and is essential for their
function. Microtubules (MTs) play a role in structural integrity, cell motility, material transport …

Despite widespread and striking examples of physiological oscillations, their functional role
is often unclear. Even glycolysis, the paradigm example of oscillatory biochemistry, has seen …

Abstract Coronavirus disease 2019 (COVID-19), which is a respiratory illness associated
with high mortality, has been classified as a pandemic. The major obstacles for the clinicians …

Stress granules (SGs) are formed in the cytosol as an acute response to environmental cues
and activation of the integrated stress response (ISR), a central signaling pathway …

Randomness characterizes many processes in nature, and therefore its importance cannot
be overstated. In the present study, we investigate examples of randomness found in various …

During embryogenesis cells make fate decisions within complex tissue environments. The
levels and dynamics of transcription factor expression regulate these decisions. Here, we …

The fine balance of growth and division is a fundamental property of the physiology of cells,
and one of the least understood. Its study has been thwarted by difficulties in the accurate …

Noise is prevalent in biology and has been widely quantified using snapshot measurements.
This static view obscures our understanding of dynamic noise properties and how these …

Quiescence is a dynamic process of reversible cell cycle arrest. High-level persistent
expression of the HES1 transcriptional repressor, which oscillates with an ultradian …

Here, we study the dynamical expression of endogenously labeled Hes1, a transcriptional
repressor implicated in controlling cell proliferation, to understand how cell-cycle length …